Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
Indian Heart J. 2020 Nov-Dec;72(6):482-490. doi: 10.1016/j.ihj.2020.10.003. Epub 2020 Oct 20.
Opioids have the highest rate of illicit drug consumption after cannabis worldwide. Opium, after tobacco, is still the most commonly abused substance in the Middle East. In addition to the ease of availability, one reason for the high consumption of opium in Asian countries might be a traditional belief among Eastern people and even medical staff that opium may have ameliorating effects on cardiovascular diseases (CVDs) as well as diabetes mellitus, hypertension, and dyslipidemia. Over the last decade, many studies have been performed on humans and animals to evaluate the interplay between opium consumption and stable coronary artery disease, acute coronary syndromes, and atherosclerosis. In this review, we conclude that opium consumption should be considered a risk factor for CVDs. Healthy individuals, as well as cardiac and diabetic patients, should be informed and educated about the hazardous effects of opium consumption on cardiovascular and other chronic diseases.
阿片类药物在世界范围内的非法药物消费中仅次于大麻，居首位。在中东，鸦片仍然是仅次于烟草的最常被滥用的物质。除了易于获得之外，亚洲国家鸦片消费高的另一个原因可能是东方人甚至医务人员的传统观念认为鸦片可能对心血管疾病 (CVD) 以及糖尿病、高血压和血脂异常有缓解作用。在过去的十年中，已经在人类和动物身上进行了许多研究，以评估鸦片消费与稳定型冠状动脉疾病、急性冠状动脉综合征和动脉粥样硬化之间的相互作用。在这篇综述中，我们得出结论，鸦片消费应被视为 CVD 的一个危险因素。健康个体以及心脏和糖尿病患者应该了解并认识到鸦片消费对心血管和其他慢性疾病的危害。
