Hwang Jae Yeon, Choi Kwang-Hwan, Lee Chang-Kyu
Department of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute of Agriculture and Life Science, Seoul National University, Seoul 151-921, Republic of Korea.
Department of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute of Agriculture and Life Science, Seoul National University, Seoul 151-921, Republic of Korea; Designed Animal & Transplantation Research Institute, Institute of Green Bio Science and Technology, Seoul National University, Gangwon-do 232-916, Republic of Korea.
Data Brief. 2015 Nov 29;5:1072-7. doi: 10.1016/j.dib.2015.11.019. eCollection 2015 Dec.
The data included in this article shows homologies of genes in porcine X-chromosome inactivation center, XIC, to each orthologue in human and mouse XIC. Open sequences of XIC-linked genes in human and mouse were compared to porcine genome and sequence homology of each orthologue to porcine genome was calculated. Sequence information of porcine genes encoded in the genomic regions having sequence homology with the human XIC-linked genes and their 2 Kb upstream regions were downloaded. Obtained information was used to design primer pairs for expression and methylation pattern analyses of XIC-linked genes in pigs. The data represented in here is related and applied to the research article entitled "Dosage compensation of X-chromosome inactivation center, XIC,-linked genes in porcine preimplantation embryos: Non-chromosome wide initiation of X-chromosome inactivation in blastocysts", published in Mechanisms of Development Hwang et al., 2015 [1].
本文所包含的数据显示了猪X染色体失活中心（XIC）中的基因与人类和小鼠XIC中各直系同源基因的同源性。将人类和小鼠中与XIC连锁的基因的开放序列与猪基因组进行比较，并计算每个直系同源基因与猪基因组的序列同源性。下载了猪基因组中与人类XIC连锁基因及其2 kb上游区域具有序列同源性的基因组区域所编码的猪基因的序列信息。所获得的信息用于设计引物对，以分析猪中与XIC连锁基因的表达和甲基化模式。此处呈现的数据与发表于《发育机制》（Hwang等人，2015年[1]）的题为“猪植入前胚胎中X染色体失活中心（XIC）连锁基因的剂量补偿：囊胚中X染色体失活的非全染色体范围起始”的研究文章相关并应用于该文章。
