Vaca Miguel, Cobeta Ignacio, Mora Elena, Reyes Pablo
Department of Otolaryngology, Hospital Universitario Ramón y Cajal, Carretera Colmenar km 9, 28034 Madrid, Spain; Universidad de Alcalá de Henares, Campus Universitario-C/19, Ctra. Madrid-Barcelona, Km 33,600, 28871 Alcalá de Henares, Madrid, Spain..
Department of Otolaryngology, Hospital Universitario Ramón y Cajal, Carretera Colmenar km 9, 28034 Madrid, Spain; Universidad de Alcalá de Henares, Campus Universitario-C/19, Ctra. Madrid-Barcelona, Km 33,600, 28871 Alcalá de Henares, Madrid, Spain.
J Voice. 2017 Jan;31(1):128.e1-128.e5. doi: 10.1016/j.jvoice.2015.12.010. Epub 2016 Jan 21.
Incomplete glottal closure is one of the key clinical aspects of presbylarynx. The objective of the present study is to determine the diagnostic yield of several tests for the assessment of glottal competence in age-related dysphonia.
Cross-sectional prospective.
One hundred and four healthy patients 65 years and older with a maximum phonation time below 12 seconds for women and 15 seconds for men were included. The glottal closure was assessed with laryngostroboscopy, and this observation was used as gold standard. Continuous light endoscopy, s/z ratio, electroglottography, and aerodynamic analysis of voice were performed, and their accuracy parameters for the diagnosis of the glottal gap in this context were calculated.
A spindle-shaped gap was observed in 47 cases. Sensitivity of vocal fold bowing to predict glottal gap in phonation was 93.6% with a negative likelihood ratio of 0.15. Specificity of s/z ratio was 91.4% with a positive likelihood ratio of 6.17. Electroglottography and aerodynamic measurements of voice resulted to be inaccurate for the diagnosis of glottal insufficiency in phonation.
Conventional endoscopy and s/z ratio are good diagnostic tests for an initial assessment of glottal insufficiency in age-related dysphonia that would allow general otolaryngologists early identification and prompt treatment of this pathology.
声门闭合不全是老年喉的关键临床特征之一。本研究的目的是确定几种用于评估与年龄相关的发声障碍中声门功能的检查的诊断效能。
横断面前瞻性研究。
纳入104名65岁及以上的健康患者,女性最大发声时间低于12秒,男性低于15秒。通过喉动态镜评估声门闭合情况,并将此观察结果用作金标准。进行连续光内镜检查、s/z比值、电声门图和嗓音空气动力学分析,并计算它们在此背景下诊断声门间隙的准确性参数。
47例观察到纺锤形间隙。声带弓曲预测发声时声门间隙的敏感性为93.6%,阴性似然比为0.15。s/z比值的特异性为91.4%,阳性似然比为6.17。电声门图和嗓音空气动力学测量结果显示对发声时声门功能不全的诊断不准确。
传统内镜检查和s/z比值是对与年龄相关的发声障碍中声门功能不全进行初步评估的良好诊断检查,这将使普通耳鼻喉科医生能够早期识别并及时治疗这种疾病。