Sabroe Ruth A, Holden Catherine R, Gawkrodger David J
Department of Dermatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, S10 2JF, UK.
Contact Dermatitis. 2016 Apr;74(4):236-41. doi: 10.1111/cod.12528. Epub 2016 Jan 25.
Essential oils are fragrance substances that are labelled on cosmetic products by their INCI names, potentially confusing consumers.
To establish whether contact allergy to essential oils might be missed if not specifically tested for.
We tested 471 patients with 14 essential oils and 2104 patients with Melaleuca alternifolia oil between January 2008 and June 2014. All patients were tested with fragrance mix I, fragrance mix II, hydroxyisohexyl 3-cyclohexene carboxaldehyde, and Myroxylon pereirae. Three hundred and twenty-six patients were tested with hydroperoxides of limonene and linalool.
Thirty-four patients had a +/++/+++ reaction to at least one essential oil. Eleven had no reaction to any of the six marker fragrance substances. Thus, 4 of 11 positive reactions to M. alternifolia oil, 2 of 7 reactions to Cymbopogon flexuosus oil, 1 of 5 reactions to Cananga odorata oil, 3 of 4 reactions to Santalum album oil and 2 of 3 reactions to Mentha piperita oil would have been missed without individual testing.
A small number of patients who are allergic to essential oils could be missed if these are not specifically tested. Labelling by INCI names means that exposure may not be obvious. Careful inspection of so-called 'natural' products and targeted testing is recommended.
香精油是一种香料物质，在化妆品上以其国际化妆品原料命名（INCI）进行标注，这可能会使消费者感到困惑。
确定如果不对香精油进行专门检测，是否会漏诊对其的接触性过敏。
在2008年1月至2014年6月期间，我们对471例患者使用14种香精油进行检测，对2104例患者使用互叶白千层油进行检测。所有患者均接受香料混合物I、香料混合物II、羟基异己基3 - 环己烯甲醛和秘鲁香脂检测。326例患者接受柠檬烯和芳樟醇氢过氧化物检测。
34例患者对至少一种香精油有+/++/+++反应。11例患者对六种标记香料物质均无反应。因此，如果不进行单独检测，互叶白千层油11例阳性反应中的4例、弯曲香茅油7例反应中的2例、依兰油5例反应中的1例、檀香木油4例反应中的3例以及薄荷油3例反应中的2例将会漏诊。
如果不对香精油进行专门检测，可能会漏诊少数对其过敏的患者。以INCI名称标注意味着接触情况可能不明显。建议仔细检查所谓的“天然”产品并进行针对性检测。
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