Gerasimova M V, Rozanova L M, Smirnova A I, Krotova T A, Shcherbakova E G
Vopr Onkol. 1977;23(4):30-5.
In sera of patients with acute leucosis the authors have determined antibodies to alpha-toxin, streptolysin-O, the complement, lysosyme. B-lysins and C-reactive protein. It was found that the indices of immune reactivity in patients with acute leucosis are dependent on a morphological variant of the disease, the duration of the conducted therapy and presence of complications. The most high immunity indices in patients with acute leucosis were observed in a primary active stage of the disease and during the period of remission. Considerable reduction of the immunity was noted in the terminal stage of the disease.
作者测定了急性白血病患者血清中抗α毒素、抗链球菌溶血素O、补体、溶菌酶、B-溶素和C反应蛋白的抗体。结果发现，急性白血病患者的免疫反应指标取决于疾病的形态学变异、所进行治疗的持续时间以及并发症的存在情况。急性白血病患者在疾病的原发性活动期和缓解期免疫指标最高。在疾病的终末期，免疫力显著下降。
