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甲状腺眼病眼眶减压术后中央视网膜静脉阻塞得以缓解

Central Retinal Vein Occlusion Resolving After Orbital Decompression in Thyroid Eye Disease.

作者信息

Grob Seanna R, Yoon Michael K

机构信息

*Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts; †Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; and ‡Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, U.S.A.

出版信息

Ophthalmic Plast Reconstr Surg. 2017 May/Jun;33(3S Suppl 1):S188-S190. doi: 10.1097/IOP.0000000000000635.

Abstract

A 49-year-old male presented with proptosis and was found to have optic nerve edema with peripapillary hemorrhages. Diagnostic testing showed a suppressed thyroid-stimulating hormone. CT orbits showed homogenous tendon-sparing enlargement of the medial and inferior rectus muscles, characteristic of thyroid eye disease. Intravenous methylprednisolone was administered given the concern for compressive optic neuropathy. He initially had improvement of his symptoms, so orbital decompression was deferred. Subsequently he presented with worsening diplopia and right proptosis, a new afferent pupillary defect, and a cecocentral visual field defect. Dilated examination revealed significant optic nerve head edema and diffuse retinal hemorrhages in all 4 quadrants consistent with a central retinal vein occlusion. The patient underwent an urgent 3-wall orbital decompression on the right. Close follow up postoperatively showed resolution of the central retinal vein occlusion and the associated optic disc edema, peripapillary hemorrhages, and macular edema. Orbital decompression is known to improve many manifestations of thyroid eye disease, but this is the first report of orbital decompression resulting in resolution of a central retinal vein occlusion.

摘要

一名49岁男性因眼球突出就诊,检查发现视神经水肿伴视乳头周围出血。诊断性检查显示促甲状腺激素水平降低。眼眶CT显示内直肌和下直肌均匀性增粗,肌腱未受累,符合甲状腺眼病的特征。鉴于存在压迫性视神经病变,给予静脉注射甲泼尼龙。他最初症状有所改善,因此推迟了眼眶减压手术。随后,他出现复视加重和右眼突出,出现新的传入性瞳孔障碍以及中心暗点视野缺损。散瞳检查发现视神经乳头明显水肿,四个象限均有弥漫性视网膜出血,符合视网膜中央静脉阻塞。该患者接受了右侧三壁眼眶减压急诊手术。术后密切随访显示视网膜中央静脉阻塞以及相关的视盘水肿、视乳头周围出血和黄斑水肿均已消退。已知眼眶减压可改善甲状腺眼病的许多表现,但这是关于眼眶减压导致视网膜中央静脉阻塞消退的首例报道。

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