Talwar G P, Singh O, Jayashankar R, Shaha C, Suri A, Rao L V, Gaur A, Alam A, Upadhyay S N, Pal R
National Institute of Immunology, New Delhi, India.
Immunol Suppl. 1989;2:93-7; discussion 98.
Birth control vaccines constitute a new category of vaccines. Immunization with the objective of selectively blocking a physiological process differs in many respects from immunizing against pathogens. Conceptually, these widen the orbit of therapeutic intervention by immunological methods. Success recorded in making vaccines regulating fertility offers models to regulate any other physiological process in the body. At a practical level, the task of making such vaccines is beset with inherent difficulties and with new challenges. This article, dedicated to Avrion Mitchison, aims to discuss these problems and to record successes wherever achieved.
节育疫苗构成了一类新型疫苗。以选择性阻断生理过程为目标的免疫接种在许多方面不同于针对病原体的免疫接种。从概念上讲，这些疫苗拓宽了通过免疫学方法进行治疗干预的范围。在研制调节生育能力疫苗方面取得的成功为调节身体任何其他生理过程提供了范例。在实际操作层面，研制此类疫苗的任务面临着固有的困难和新的挑战。本文献给阿夫里翁·米奇森，旨在探讨这些问题并记录已取得的成功。
