Pilmis B, Mizrahi A, Laincer A, Couzigou C, El Helali N, Nguyen Van J-C, Abassade P, Cador R, Le Monnier A
Équipe mobile de microbiologie clinique, groupe hospitalier Paris-Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France.
Laboratoire de microbiologie clinique et dosage des anti-infectieux, groupe hospitalier Paris-Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France.
Med Mal Infect. 2016 Feb;46(1):44-8. doi: 10.1016/j.medmal.2015.12.012. Epub 2016 Jan 22.
We aimed to assess the clinical presentation, microbial etiology and outcome of patients presenting with infective endocarditis (IE).
We conducted a four-year retrospective study including all patients presenting with IE.
We included 121 patients in the study. The median age was 74.8years. Most patients had native valve IE (57%). Staphylococcus aureus accounted for 24.8% of all IE. Surgery was indicated for 70 patients (57.9%) but actually performed in only 55 (44.7%). Factors associated with surgery were younger age (P=0.002) and prosthetic valve IE (P=0.001). Risk factors associated with in-hospital mortality were diabetes mellitus (OR=3.17), chronic renal insufficiency (OR=6.62), and surgical indication (OR=3.49). Mortality of patients who underwent surgery was one sixth of that of patients with surgical indication who did not have the surgery (P<0.001).
我们旨在评估感染性心内膜炎（IE）患者的临床表现、微生物病因及预后。
我们进行了一项为期四年的回顾性研究，纳入所有IE患者。
本研究共纳入121例患者。中位年龄为74.8岁。大多数患者为自体瓣膜心内膜炎（57%）。金黄色葡萄球菌占所有IE的24.8%。70例患者（57.9%）有手术指征，但实际仅55例（44.7%）接受了手术。与手术相关的因素为年龄较小（P = 0.002）和人工瓣膜心内膜炎（P = 0.001）。与院内死亡相关的危险因素为糖尿病（OR = 3.17）、慢性肾功能不全（OR = 6.62）和手术指征（OR = 3.49）。接受手术患者的死亡率是有手术指征但未接受手术患者的六分之一（P < 0.001）。
