Kim Tae Hyun, Lee Eui-Kyung, Han Euna
Graduate School of Public Health and Institute of Health Services Research, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, South Korea.
School of Pharmacy, Sungkyunkwan University, 300 Cheonchoen-dong, Jangan-gu, Suwon, Gyeonggi-do 440-746, South Korea.
Res Social Adm Pharm. 2016 Nov-Dec;12(6):990-1003. doi: 10.1016/j.sapharm.2015.12.009. Epub 2015 Dec 29.
Overweight/obesity is a growing health risk in Korea. The impact of overweight/obesity on pharmaceutical expenditure can be larger if individuals have multiple risk factors and multiple comorbidities. The current study estimated the combined effects of overweight/obesity and other unhealthy behaviors on pharmaceutical expenditure.
An instrumental variable quantile regression model was estimated using Korea Health Panel Study data. The current study extracted data from 3 waves (2009, 2010, and 2011).
The final sample included 7148 person-year observations for adults aged 20 years or older. Overweight/obese individuals had higher pharmaceutical expenditure than their non-obese counterparts only at the upper quantiles of the conditional distribution of pharmaceutical expenditure (by 119% at the 90th quantile and 115% at the 95th). The current study found a stronger association at the upper quantiles among men (152%, 144%, and 150% at the 75th, 90th, and 95th quantiles, respectively) than among women (152%, 150%, and 148% at the 75th, 90th, and 95th quantiles, respectively). The association at the upper quantiles was stronger when combined with moderate to heavy drinking and no regular physical check-up, particularly among males.
The current study confirms that the association of overweight/obesity with modifiable unhealthy behaviors on pharmaceutical expenditure is larger than with overweight/obesity alone. Assessing the effect of overweight/obesity with lifestyle risk factors can help target groups for public health intervention programs.
超重/肥胖在韩国正成为日益严重的健康风险。如果个体存在多种风险因素和多种合并症,超重/肥胖对药物支出的影响可能会更大。本研究估计了超重/肥胖与其他不健康行为对药物支出的综合影响。
使用韩国健康面板研究数据估计工具变量分位数回归模型。本研究从3个波次(2009年、2010年和2011年)中提取数据。
最终样本包括7148个20岁及以上成年人的人年观察值。超重/肥胖个体仅在药物支出条件分布的较高分位数处比非肥胖个体有更高的药物支出(在第90分位数处高119%,在第95分位数处高115%)。本研究发现,男性在较高分位数处的关联更强(在第75、90和95分位数处分别为152%、144%和150%),高于女性(在第75、90和95分位数处分别为152%、150%和148%)。当与中度至重度饮酒和不定期进行身体检查相结合时,较高分位数处的关联更强,尤其是在男性中。
本研究证实,超重/肥胖与可改变的不健康行为对药物支出的关联大于超重/肥胖单独的影响。评估超重/肥胖与生活方式风险因素的影响有助于确定公共卫生干预项目的目标群体。