Baron J A
Department of Medicine, Dartmouth Medical School, Hanover, NH 03756.
J Clin Epidemiol. 1989;42(10):1013-20. doi: 10.1016/0895-4356(89)90167-4.
Epidemiological data on risk factors may be used by clinicians to help diagnose the presence of a disease or assess the probability of its developing in the future. However, the use of risk factor data in this way has not been well evaluated. In this report, relationships are derived between common epidemiological measures of association, such as risk ratios, and common clinically useful measures, such as the operating characteristics of tests. These indicate that even a risk factor with a high relative risk may not be effective when used clinically.
临床医生可以利用有关风险因素的流行病学数据来帮助诊断疾病的存在或评估其未来发生的可能性。然而,以这种方式使用风险因素数据尚未得到充分评估。在本报告中,我们推导了常见的流行病学关联指标(如风险比)与常见的临床有用指标(如检查的操作特征)之间的关系。这些结果表明,即使是相对风险较高的风险因素,在临床应用时也可能无效。