Kaya U, Çavuş U Y, Karakılıç M E, Erdem A B, Aydın K, Işık B, Abacıoğlu S, Büyükcam F
Department of Emergency Medicine, Zonguldak State Hospital, Zonguldak, Turkey.
Department of Emergency Medicine, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Eur J Trauma Emerg Surg. 2013 Dec;39(6):641-6. doi: 10.1007/s00068-013-0322-2. Epub 2013 Aug 22.
Abdominal trauma is the third most common cause of all trauma-related deaths in children. Liver injury is the second most common, but the most fatal injury associated with abdomen trauma. Because the liver enzymes have high sensitivity and specificity, the use of tomography has been discussed for accurate diagnosis of liver injury.
Our study was based on retrospective analyses of hemodynamically stabil patients under the age of 18 who were admitted to the emergency department with blunt abdominal trauma.
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were significantly higher as a result of liver injury. In the patients whose AST and ALT levels were lower than 40 IU/L, no liver injury was observed in the contrast-enhanced computed tomography (CT). No liver injury was detected in the patients with AST levels lower than 100 IU/L. Liver injury was detected with contrast-enhanced CT in only one patient whose ALT level was lower than 100 IU/L, but ultrasonography initially detected liver injury in this patient.
According to our findings, abdominal CT may not be necessary to detect liver injury if the patient has ALT and AST levels below 100 IU/L with a negative abdominal USG at admission and during follow-up.
腹部创伤是儿童所有创伤相关死亡的第三大常见原因。肝损伤是第二常见的,但却是与腹部创伤相关的最致命损伤。由于肝酶具有高敏感性和特异性,因此已讨论使用断层扫描来准确诊断肝损伤。
我们的研究基于对18岁以下因钝性腹部创伤入住急诊科且血流动力学稳定的患者进行回顾性分析。
肝损伤导致天冬氨酸转氨酶(AST)和丙氨酸转氨酶(ALT)水平显著升高。在AST和ALT水平低于40 IU/L的患者中,对比增强计算机断层扫描(CT)未观察到肝损伤。AST水平低于100 IU/L的患者未检测到肝损伤。仅1例ALT水平低于100 IU/L的患者通过对比增强CT检测到肝损伤,但该患者最初通过超声检查检测到肝损伤。
根据我们的研究结果,如果患者入院时及随访期间ALT和AST水平低于100 IU/L且腹部超声检查结果为阴性,则可能无需进行腹部CT检查来检测肝损伤。