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胎儿肿瘤的超声诊断与评估

Ultrasound diagnosis and evaluation of fetal tumors.

作者信息

Kurjak A, Zalud I, Jurković D, Alfirević Z, Tomić K

机构信息

Ultrasonic Institute, University of Zagreb, Yugoslavia.

出版信息

J Perinat Med. 1989;17(3):173-93. doi: 10.1515/jpme.1989.17.3.173.

Abstract

Fetal tumors represent a rare and heterogeneous group of abnormalities. A significant proportion of them can now be diagnosed by using modern high resolution ultrasonic equipment. During 15 years there were 57 fetal tumours detected prenatally. Hygroma colli is the most frequent fetal tumor. It should be emphasized that cystic hygroma generally carries poor prognosis, and after an early diagnosis, termination of pregnancy is most logical approach. Contrary to the general opinion our own experience showed that there are cases in which prognosis could be much better as illustrated with our 4 cases. All of the treated fetuses, after surgical resection, had normal development and are now on the age of 5, 4, 3 and 2 years of life. An ovarian cyst can be suspected if a fluid-filled structure is visualized next to a fetal kidney and female external genitalia are recognizable. The ultrasound finding suggestive of an ovarian cyst is that of a pelvic cystic or complex mass in a female fetus with normal kidneys and urinary bladder and a normal gastrointestinal tract. In most cases, the normal course of fetal ovarian cyst is a spontaneous intrauterine or postnatal involution. Prenatal diagnosis improves neonatal outcome by allowing an appropriate choice of the optimal time, mode and place of delivery in order to avoid accidental and unexpected intrapartum and postnatal complications. The management of a fetus affected by an ovarian cyst depends on the size and on the echo-pattern of the cyst. It remains unclear whether in utero puncture of the cyst and evacuation of its content should be justified in cases of particularly large ovarian cyst. In our opinion intrauterine procedure can be attempted in the presence of large cyst fulfilling the fetal abdomen. We have treated actively two cases of large ovarian cysts by ultrasonically guided puncture before delivery and both fetuses underwent surgery later without complications. If properly performed puncture of the cyst seems to be a low risk procedure in comparison to potential problems that cyst may cause to the fetus or by causing dystocia. Sacrococcygeal teratoma represents the most frequent tumor in the fetuses and newborns. Prenatal diagnosis is usually simple and based on the visualization of tumor of variable size and internal structure. Tumors may appear as completely cystic, mixed or predominantly solid with obvious calcifications. Cystic and calcified tumors are most likely to be benign. Obstetrical management of sacrococcygeal teratoma depends on numerous parameters which include size and texture of the tumor, and gestational age.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

胎儿肿瘤是一组罕见且异质性的异常情况。现在,其中很大一部分可以通过使用现代高分辨率超声设备进行诊断。在15年期间,产前共检测出57例胎儿肿瘤。颈部水囊瘤是最常见的胎儿肿瘤。应该强调的是,囊性水囊瘤通常预后较差,早期诊断后,终止妊娠是最合理的方法。与普遍看法相反,我们自己的经验表明,有些病例的预后可能好得多,比如我们的4个病例。所有接受治疗的胎儿在手术切除后发育正常,现在分别为5岁、4岁、3岁和2岁。如果在胎儿肾脏旁看到一个充满液体的结构,且可识别出女性外生殖器,则可怀疑为卵巢囊肿。提示卵巢囊肿的超声表现是,在肾脏和膀胱及胃肠道正常的女性胎儿中,盆腔出现囊性或混合性肿块。在大多数情况下,胎儿卵巢囊肿的正常病程是在宫内或出生后自行消退。产前诊断通过允许适当选择最佳分娩时间、方式和地点来改善新生儿结局,以避免意外和意想不到的产时及产后并发症。受卵巢囊肿影响的胎儿的处理取决于囊肿的大小和回声模式。对于特别大的卵巢囊肿,子宫内穿刺囊肿并抽出其内容物是否合理仍不清楚。我们认为,在囊肿充满胎儿腹部的情况下,可以尝试进行宫内操作。我们积极治疗了2例大卵巢囊肿,在分娩前通过超声引导穿刺,两个胎儿后来都顺利接受了手术,无并发症。与囊肿可能给胎儿带来的潜在问题或导致难产相比,如果操作得当,囊肿穿刺似乎是一种低风险的操作。骶尾部畸胎瘤是胎儿和新生儿中最常见的肿瘤。产前诊断通常很简单,基于对大小和内部结构各异的肿瘤的可视化。肿瘤可能表现为完全囊性、混合性或主要为实性,伴有明显钙化。囊性和钙化性肿瘤最有可能是良性的。骶尾部畸胎瘤的产科处理取决于许多参数,包括肿瘤的大小和质地以及孕周。(摘要截取自400字)

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