Rawal Gautam, Yadav Sankalp, Wani Umar Rasool, Ambastha Alok Kumar
Attending Consultant, Department of Critical Care, Rockland Hospital , Qutab Institutional Area, New Delhi, India .
General Duty Medical Officer-II, Chest Clinic , Moti Nagar, North MCD, New Delhi, India .
J Clin Diagn Res. 2015 Dec;9(12):OD06-7. doi: 10.7860/JCDR/2015/16999.6966. Epub 2015 Dec 1.
Herpes simplex virus encephalitis (HSVE) is one of the most potentially fatal infectious disease that should be detected as early as possible. The combination of clinical history and examination, brain computed tomography or magnetic resonance imaging (MRI) and lumbar puncture have been used to establish a diagnosis. The authors present a case of HSVE with normal CSF analysis, but typical MRI findings consistent with HSE and CSF PCR positive for Herpes simplex virus1 DNA, who responded to Acyclovir therapy with complete recovery.
单纯疱疹病毒性脑炎（HSVE）是最具潜在致命性的传染病之一，应尽早检测。临床病史与检查、脑部计算机断层扫描或磁共振成像（MRI）以及腰椎穿刺相结合已被用于确诊。作者报告了一例单纯疱疹病毒性脑炎病例，其脑脊液分析结果正常，但MRI表现典型，符合单纯疱疹性脑炎，脑脊液PCR检测单纯疱疹病毒1型DNA呈阳性，该患者接受阿昔洛韦治疗后完全康复。
