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腹主动脉分叉对宫颈癌放射治疗计划的影响

Implication of Bifurcation of Abdominal Aorta for Radiotherapy Planning for Cervical Cancers.

作者信息

Ponni Thiru Raju Arul, Avinash Handanakere Udayashankara, Janaki Manur Gururajachar, Koushik Agrahara Srinivas Kirthi, Somashekar Mohan Kumar

机构信息

Associate Professor, Department of Radiation Oncology, M.S. Ramaiah Medical College Hospital , Bangalore, India .

Senior Resident, Department of Radiation Oncology, St John's Medical College Hospital , Bangalore, India .

出版信息

J Clin Diagn Res. 2015 Dec;9(12):XC01-XC03. doi: 10.7860/JCDR/2015/15051.6902. Epub 2015 Dec 1.

Abstract

INTRODUCTION

External Beam Radiotherapy plays a major role in the management of Carcinoma Cervix. The Radiotherapy treatment portals are designed to adequately cover the gross disease and areas of microscopic spread. The upper border of Radiotherapy field is traditionally placed at the level of L4-L5 intervertebral space to cover the common iliac nodal area. It is determined based on anatomical and surgical series which have shown that division of Abdominal aorta occurs at that level.

AIM

To study the level of the division of abdominal aorta in relation to the lumbar vertebral levels. To propose the change in the upper border of Radiotherapy portals used in the treatment of Cervical Cancers.

MATERIALS AND METHODS

Patients who underwent Radiotherapy for Cervical Cancer from December 2010 to January 2012 formed the subjects of this prospective study. All the patients underwent aquaplast immobilization in supine position and contrast enhanced Computed Tomography (CT) simulation for Radiotherapy planning following bladder protocol. The Radiotherapy planning was done on commercial treatment planning system, Prowess version 4.71. The level of division of Abdominal Aorta into right and left Common Iliac arteries with respect to vertebral level was determined and studied.

RESULTS

The division of abdominal aorta into common iliac arteries occurred at the level of L3-L4 intervertebral space, in front of body of L4 vertebra and L4-L5 intervertebral space in 53.84%, 30.76% and 15.40% of the patients respectively.

CONCLUSION

The division of abdominal aorta occurs at a higher level than L4-L5 intervertebral space in majority of patients. It is highly recommended to use CT scan based planning. However, in institutes where there are no facilities for CT based planning, it is advisable to shift the upper border of Radiotherapy treatment portal above the L3-L4 intervertebral space for delivering adequate doses to the common iliac lymphnodes.

摘要

引言

外照射放疗在子宫颈癌的治疗中起着重要作用。放疗治疗野的设计旨在充分覆盖大体肿瘤及微小播散区域。传统上,放疗野的上界置于L4 - L5椎间隙水平,以覆盖髂总淋巴结区域。这是根据解剖学和手术系列研究确定的,这些研究表明腹主动脉在该水平处分支。

目的

研究腹主动脉分支水平与腰椎椎体水平的关系。提出用于宫颈癌治疗的放疗野上界的改变。

材料与方法

2010年12月至2012年1月接受宫颈癌放疗的患者构成了本前瞻性研究的对象。所有患者均在仰卧位接受水凝胶固定,并按照膀胱方案进行增强CT模拟以进行放疗计划。放疗计划在商业治疗计划系统Prowess版本4.71上完成。确定并研究腹主动脉分为左右髂总动脉的水平与椎体水平的关系。

结果

腹主动脉分为髂总动脉的水平分别在L3 - L4椎间隙、L4椎体前方和L4 - L5椎间隙的患者比例分别为53.84%、30.76%和15.40%。

结论

大多数患者腹主动脉分支水平高于L4 - L5椎间隙。强烈建议使用基于CT扫描的计划。然而,在没有基于CT计划设施的机构中,建议将放疗治疗野的上界移至L3 - L4椎间隙上方,以便向髂总淋巴结给予足够剂量。

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