Clark R A
J R Coll Surg Edinb. 1989 Aug;34(4):177-84.
Asthma and chronic obstructive pulmonary disease (COPD), i.e. chronic bronchitis and emphysema are common. The pathological and clinical features of these diseases are described. Ventilatory function, lung volumes and 6-min walking tests are used to assess respiratory function while blood gas estimations are essential when managing respiratory failure. The causal mechanisms of respiratory failure are described. In COPD careful assessment with maximization of respiratory function is essential preoperatively. Continued smoking increases postoperative complications sixfold. Bronchial irritability, common in asthma and COPD, increases the anaesthetic risks while many anaesthetic agents adversely affect respiratory function. Postoperative pulmonary complications remain common particularly in COPD. The hypoxia occurring in the first 2 hours post-surgery is usually more pronounced in COPD. Careful postoperative monitoring with aggressive treatment of any complications is essential in these patients. Surgical treatment may significantly improve respiratory function in some patients with bullous emphysema.
哮喘和慢性阻塞性肺疾病(COPD),即慢性支气管炎和肺气肿很常见。文中描述了这些疾病的病理和临床特征。通气功能、肺容量和6分钟步行试验用于评估呼吸功能,而在处理呼吸衰竭时,血气测定至关重要。文中描述了呼吸衰竭的病因机制。对于COPD患者,术前进行仔细评估并使呼吸功能最大化至关重要。持续吸烟会使术后并发症增加六倍。支气管激惹在哮喘和COPD中很常见,会增加麻醉风险,而许多麻醉药物会对呼吸功能产生不利影响。术后肺部并发症仍然很常见,尤其是在COPD患者中。术后最初2小时出现的低氧血症在COPD患者中通常更为明显。对这些患者进行仔细的术后监测并积极治疗任何并发症至关重要。手术治疗可能会显著改善一些大疱性肺气肿患者的呼吸功能。