Rezaiguia S, Jayr C
Service d'anesthésie-réanimation, hôpital Henri-Mondor, Créteil, France.
Ann Fr Anesth Reanim. 1996;15(5):623-46. doi: 10.1016/0750-7658(96)82128-9.
Abdominal surgery, especially upper abdominal surgical procedures are known to adversely affect pulmonary function. Pulmonary complications are the most frequent cause of postoperative morbidity and mortality. This review article aimed to analyse the incidence and risk factors for postoperative pulmonary morbidity and their prevention. The most important means for preoperative assessment is the clinical examination; pulmonary function tests (spirometry) are not reliably predictive for postoperative pulmonary complications. Age, type of surgical procedure, smoking and nutritional state have all been identified as potential predictors for postoperative complications. However, usually there is not enough preoperative time available to obtain beneficial effects of stopping smoking and improvement of nutritional state. In patients with COPD, a preoperative multidisciplinary evaluation including the primary care physician, pulmonologist/intensivist, anesthesiologist and surgeon is required. Consensus as to preoperative physiologic state, therapeutic preparation, and postoperative management is essential. Simple spirometry and arterial blood gas analysis are indicated in patients exhibiting symptoms of obstructive airway disease. There are no values that contra-indicate an essential surgical procedure. Smoking should stop at least 8 weeks preoperatively. Preoperative therapy for elective surgery with antibiotics, beta2-agonist, or anticholinergic bronchodilator aerosols, as well as training in cough and lung expansion techniques should begin at least 24 to 48 hours preoperatively. Postoperative therapy should be continued for 3 to 5 days. Usually, anaesthesia is responsible for early complications, whereas surgical procedures are often associated with delayed morbidity. Laparoscopic procedures are recommended, as postoperative morbidity and hospital stay seem reduced in patients without COPD. Regional anaesthesia is given as having less adverse effects on pulmonary function than general anaesthesia. However, for unknown reasons these benefits are not associated with a decrease in postoperative respiratory complications. Moreover, the quality or the type of postoperative analgesia does not influence postoperative respiratory morbidity. Postoperatively, oxygen administration increases SaO2, but cannot abolish desaturation due to obstructive apnea. The various techniques of physiotherapy (chest physiotherapy, incentive spirometry, continuous positive airway pressure breathing) seem to be equivalent in efficacy; but intermittent positive pressure breathing has no advantages, compared with the other treatments and could even be deleterious. Chest physiotherapy and incentive spirometry are the most practical methods available for decreasing secretion contents of airways, whereas continuous positive airway pressure breathing is efficient on atelectasis. In stage II or III COPD patients, admission in a intensive therapy unit and prolonged mechanical ventilation may be required.
腹部手术,尤其是上腹部手术,已知会对肺功能产生不利影响。肺部并发症是术后发病和死亡的最常见原因。这篇综述文章旨在分析术后肺部发病的发生率、危险因素及其预防措施。术前评估的最重要手段是临床检查;肺功能测试(肺活量测定)对术后肺部并发症的预测并不可靠。年龄、手术类型、吸烟和营养状况均已被确定为术后并发症的潜在预测因素。然而,通常术前没有足够的时间来获得戒烟和改善营养状况的有益效果。对于慢性阻塞性肺疾病(COPD)患者,需要进行包括初级保健医生、肺科医生/重症监护医生、麻醉医生和外科医生在内的术前多学科评估。就术前生理状态、治疗准备和术后管理达成共识至关重要。对于有阻塞性气道疾病症状的患者,应进行简单的肺活量测定和动脉血气分析。没有任何数值可作为必要手术的禁忌。术前至少应戒烟8周。择期手术的术前治疗,包括使用抗生素、β2受体激动剂或抗胆碱能支气管扩张剂气雾剂,以及咳嗽和肺扩张技术训练,应至少在术前24至48小时开始。术后治疗应持续3至5天。通常,麻醉是早期并发症的原因,而手术操作往往与延迟发病有关。推荐采用腹腔镜手术,因为在没有COPD的患者中,术后发病率和住院时间似乎会降低。与全身麻醉相比,区域麻醉对肺功能的不良影响较小。然而,出于未知原因,这些益处与术后呼吸并发症的减少并无关联。此外,术后镇痛的质量或类型并不影响术后呼吸发病率。术后吸氧可提高动脉血氧饱和度(SaO2),但无法消除因阻塞性呼吸暂停导致的血氧饱和度下降。各种物理治疗技术(胸部物理治疗、激励性肺活量测定、持续气道正压通气)在疗效上似乎相当;但与其他治疗方法相比,间歇正压通气并无优势,甚至可能有害。胸部物理治疗和激励性肺活量测定是减少气道分泌物最实用的方法,而持续气道正压通气对肺不张有效。对于II期或III期COPD患者可能需要入住重症监护病房并延长机械通气时间。