Chaiwong Tarinee, Srivoramas Thunyakarn, Sebsumran Plalakorn, Panya Marutpong, Wanram Surasak, Panomket Pawana
J Med Assoc Thai. 2016 Jan;99 Suppl 1:S7-11.
The blowfly, Chrysomya megacephala, is distributed worldwide. Previous studies found maggot excretions-secretions from other blowfly species inhibited pro-inflammatory response and antimicrobial activity.
This study aimed to test the bactericidal activity of excretions-secretions from C. megacephala larvae.
A total of 1,500 3-day-old larvae were used to collect excretions-secretions (ES) modified by the Barnes method. The bactericidal activity ofthe excretions-secretions was test by Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli using suitable liquid culture assay. Scanning electron microscope (SEM) was used to investigate the morphological change ofthe bacteria.
E. coli were significantly inhibited by excretions-secretions from C. megacephala larvae. P. aeruginosa and S. aureus were not found to inhibit growth.
The excretions-secretions from C. megacephala larvae may have a medical property for the inhibition of bacterial growth.
大头金蝇在全球范围内均有分布。先前的研究发现，其他蝇类物种的蛆排泄物-分泌物可抑制促炎反应和抗菌活性。
本研究旨在测试大头金蝇幼虫排泄物-分泌物的杀菌活性。
总共使用1500只3日龄幼虫，采用巴恩斯法收集排泄物-分泌物（ES）。通过合适的液体培养试验，用铜绿假单胞菌、金黄色葡萄球菌和大肠杆菌测试排泄物-分泌物的杀菌活性。使用扫描电子显微镜（SEM）研究细菌的形态变化。
大头金蝇幼虫的排泄物-分泌物可显著抑制大肠杆菌。未发现其对铜绿假单胞菌和金黄色葡萄球菌的生长有抑制作用。
大头金蝇幼虫的排泄物-分泌物可能具有抑制细菌生长的药用特性。
