Dimitrov G, Garnizov T, Frundeva B, Musseva A, Dimitrov A
Akush Ginekol (Sofiia). 2015;54 Suppl 2:3-9.
Intrauterine fetal death is an agonizing, often unpredictable event. Autopsies of stillborn fetuses, including placentas, umbilical cord and fetal membranes, are performed to clarify the cause of death. Autopsy results are not always easily understood by the patients and difficult to clarify by the specialists.
To evaluate the macroscopic pathological and histopathological changes in placenta, umbilical cord and fetal membranes as a factor in the pathogenesis of intrauterine fetal death.
Retrospective review of 129 autopsy reports of singleton stillborn fetuses and placentas from 23 to 41 weeks of gestation.
Macroscopic and histopathological findings in the placenta, often in combination with inflammatory changes prevailing in premature cases, while macroscopic and histopathological findings in umbilical cord predominate in term stillborn. In 11% of cases there were no specific pathological findings.
Pathological analysis of the placenta is essential for clarifying the pathogenesis of stillbirths. Simplifying the classification of pathological results of fetal appendages at autopsy categories--changes in the placenta, changes in the umbilical cord and inflammatory changes may contribute to easier interpretation and allows for comparison of results.
胎儿宫内死亡是一个令人痛苦且往往不可预测的事件。对死产胎儿进行尸检，包括胎盘、脐带和胎膜，以明确死亡原因。尸检结果患者往往不易理解，专家也难以阐明。
评估胎盘、脐带和胎膜的宏观病理及组织病理学变化作为胎儿宫内死亡发病机制的一个因素。
回顾性分析129例孕23至41周单胎死产胎儿及胎盘的尸检报告。
胎盘的宏观和组织病理学发现，常与早产病例中普遍存在的炎症变化相结合，而脐带的宏观和组织病理学发现在足月死产中占主导。11%的病例没有特异性病理发现。
胎盘的病理分析对于阐明死产的发病机制至关重要。将尸检时胎儿附属物的病理结果分类简化为——胎盘变化、脐带变化和炎症变化，可能有助于更轻松地解读，并便于结果比较。
