Blümel Juan E, Fica Juan, Chedraui Peter, Mezones-Holguín Edward, Zuñiga María C, Witis Silvina, Vallejo María S, Tserotas Konstantinos, Sánchez Hugo, Onatra William, Ojeda Eliana, Mostajo Desireé, Monterrosa Alvaro, Lima Selva, Martino Mabel, Hernández-Bueno José A, Gómez Gustavo, Espinoza María T, Flores Daniel, Calle Andrés, Bravo Luz M, Benítez Zully, Bencosme Ascanio, Barón Germán, Aedo Sócrates
1Universidad de Chile, Santiago de Chile, Chile 2Clínica AVANSALUD, Santiago de Chile, Chile 3Universidad Católica de Santiago de Guayaquil, Hospital Enrique C. Sotomayor, Guayaquil, Ecuador 4Instituto Nacional de Salud, Lima, Perú 5Universidad Nacional de Cuyo, Mendoza, Argentina 6Hospital de Clínicas, Buenos Aires, Argentina 7Universidad de Panamá, Panamá 8Clínica SOLCA, Machala, Ecuador 9Universidad de Ciencias Aplicadas y Ambientales, Bogotá, Colombia 10Universidad Andina del Cusco, Cusco, Perú 11UDIME, Santa Cruz de la Sierra, Bolivia 12Universidad de Cartagena, Cartagena de Indias, Colombia 13Facultad de Medicina CLAEH, Punta del Este, Uruguay 14Universidad Nacional de Rosario, Rosario, Argentina 15Atención Médica Integral para la Mujer, Naucalpan, México 16Universidad del Valle, Cali, Colombia 17Instituto de Endocrinología, Cochabamba, Bolivia 18Universidad Diego Portales, Santiago, Chile 19Universidad Central del Ecuador, Quito, Ecuador 20Universidad de Guadalajara, Gaudalajara, México 21Universidad Nacional de Asunción, Asunción, Paraguay 22Hospital Metropolitano de Santiago, Santiago de los Caballeros, República Dominicana 23Universidad El Bosque, Bogotá, Colombia.
Menopause. 2016 May;23(5):488-93. doi: 10.1097/GME.0000000000000575.
The aim of the study was to evaluate the association between sedentary lifestyle and the severity of menopausal symptoms and obesity in middle-aged women.
The Menopause Rating Scale, the Goldberg Anxiety and Depression Scale, and the Athens Insomnia Scale were administered to 6,079 Latin American women aged 40 to 59 years. Sedentary lifestyle was defined as fewer than three weekly, 30-minute periods of physical activity.
Sedentary women had more severe menopausal symptoms (total Menopause Rating Scale score: 9.57 ± 6.71 vs 8.01 ± 6.27 points, P < 0.0001) and more depressive symptoms (Goldberg), anxiety (Goldberg), and insomnia (Athens Scale) compared with non-sedentary women. They also had greater mean waist circumference (86.2 ± 12.3 vs 84.3 ± 1.8 cm, P < 0.0001) and a higher prevalence of obesity (20.9% vs 14.3%, P < 0.0001). Logistic regression analysis showed that both obesity (odds ratio [OR] 1.52; 95% CI, 1.32-1.76) and severe menopausal symptoms (OR 1.28; 95% CI, 1.06-1.53), including insomnia and depressive mood, were positively associated with a sedentary lifestyle. Having a stable partner (OR 0.85; 95% CI, 0.76-0.96), using hormone therapy (OR 0.75; 95% CI, 0.64-0.87) and having a higher educational level (OR 0.66; 95% CI, 0.60-0.74) were negatively related to sedentary lifestyle.
There was a high prevalence of sedentary lifestyle in this middle-aged Latin American female sample which was associated with more severe menopausal symptoms and obesity.
本研究旨在评估中年女性久坐不动的生活方式与更年期症状严重程度及肥胖之间的关联。
对6079名年龄在40至59岁的拉丁美洲女性进行了更年期评定量表、戈德堡焦虑抑郁量表和雅典失眠量表的测评。久坐不动的生活方式定义为每周进行体育活动的时间少于3个30分钟时段。
与非久坐女性相比，久坐女性有更严重的更年期症状（更年期评定量表总分：9.57±6.71分对8.01±6.27分，P<0.0001），以及更多的抑郁症状（戈德堡量表）、焦虑症状（戈德堡量表）和失眠症状（雅典量表）。她们的平均腰围也更大（86.2±12.3厘米对84.3±1.8厘米，P<0.0001），肥胖患病率更高（20.9%对14.3%，P<0.0001）。逻辑回归分析表明，肥胖（比值比[OR]1.52；95%置信区间，1.32 - 1.76）和严重的更年期症状（OR 1.28；95%置信区间，1.06 - 1.53），包括失眠和抑郁情绪，均与久坐不动的生活方式呈正相关。有稳定伴侣（OR 0.85；95%置信区间，0.76 - 0.96）、使用激素疗法（OR 0.75；95%置信区间，0.64 - 0.87）以及教育水平较高（OR 0.66；95%置信区间，0.60 - 0.74）与久坐不动的生活方式呈负相关。
在这个中年拉丁美洲女性样本中，久坐不动的生活方式患病率很高，且与更严重的更年期症状和肥胖有关。
