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美国医护人员结核菌素皮肤试验阴性与QuantiFERON干扰素γ释放试验结果逆转的预测

Negative Tuberculin Skin Test and Prediction of Reversion of QuantiFERON Interferon Gamma Release Assay in US Healthcare Workers.

作者信息

Thanassi Wendy, Noda Art, Hernandez Beatriz, Friedman Leah, Dorman Susan, Yesavage Jerome

机构信息

1Occupational Health Service,Veterans Affairs Health Care System,Palo Alto,California.

4War Related Illness and Injury Study Center and Mental Illness Research Education and Clinical Center,Department of Veterans Affairs,Palo Alto,California.

出版信息

Infect Control Hosp Epidemiol. 2016 Apr;37(4):478-82. doi: 10.1017/ice.2015.324. Epub 2016 Jan 28.

Abstract

QuantiFERON tuberculosis tests (QFT) reverted in (612) 77% of 1,094 low-risk healthcare workers (HCW) testing less than 1.16 IU/mL. Of HCW testing greater than 1.1 IU/mL, 33 (59%) of 56 with negative tuberculin skin tests (TST) reverted vs 8 (6%) of 125 with positive TSTs. Retesting low-risk QFT-positive and TST-negative HCW is prudent.

摘要

在1094名检测值低于1.16国际单位/毫升的低风险医护人员中,结核感染QuantiFERON检测(QFT)结果转阴的占77%(612人)。在结核菌素皮肤试验(TST)阴性且检测值大于1.1国际单位/毫升的医护人员中,56人中有33人(59%)QFT结果转阴;而在TST阳性的125人中,只有8人(6%)QFT结果转阴。对QFT阳性且TST阴性的低风险医护人员进行重新检测是明智的。

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