进行性核上性麻痹和血管性帕金森综合征中的磁共振帕金森综合征指数
Magnetic resonance parkinsonism index in progressive supranuclear palsy and vascular parkinsonism.
作者信息
Mostile Giovanni, Nicoletti Alessandra, Cicero Calogero Edoardo, Cavallaro Tiziana, Bruno Elisa, Dibilio Valeria, Luca Antonina, Sciacca Giorgia, Raciti Loredana, Contrafatto Donatella, Chiaramonte Ignazio, Zappia Mario
机构信息
Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
出版信息
Neurol Sci. 2016 Apr;37(4):591-5. doi: 10.1007/s10072-016-2489-x. Epub 2016 Jan 28.
To investigate accuracy of the magnetic resonance parkinsonism index (MRPI) in differentiating progressive supranuclear palsy (PSP) from vascular parkinsonism (VP). We retrospectively analyzed radiological data of 12 PSP patients and 17 VP patients group-matched by age and sex who performed a standardized brain magnetic resonance imaging (MRI). Analysis of selected structures morphometry was performed to all study subjects and the MRPI was calculated for each selected patient. MRI midbrain area as well as superior cerebellar peduncle width were significantly lower in PSP patients compared to VP subjects. MRPI was significantly larger in PSP patients compared to VP subjects. MRPI value ≥13 distinguished the two groups with a sensitivity of 100 % (95 % CI 69.9-100) and a specificity of 100 % (95 % CI 77.1-100). MRPI may represent an accurate tool in differentiating PSP from VP.
为研究磁共振帕金森综合征指数（MRPI）在鉴别进行性核上性麻痹（PSP）与血管性帕金森综合征（VP）方面的准确性。我们回顾性分析了12例PSP患者和17例按年龄和性别匹配的VP患者的放射学数据，这些患者均接受了标准化脑磁共振成像（MRI）检查。对所有研究对象进行了选定结构形态学分析，并为每位选定患者计算了MRPI。与VP患者相比，PSP患者的MRI中脑面积以及上小脑脚宽度显著更低。与VP患者相比，PSP患者的MRPI显著更大。MRPI值≥13区分两组的灵敏度为100%（95%CI 69.9 - 100），特异度为100%（95%CI 77.1 - 100）。MRPI可能是鉴别PSP与VP的一种准确工具。
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