Torres Alejandro J, McElhinney Doff B, Anderson Brett R, Turner Mariel E, Crystal Matthew A, Timchak Donna M, Vincent Julie A
Morgan Stanley Children's Hospital of New York, Columbia University Medical Center, New York, New York.
Stanford University Medical Center, Palo Alto, California.
J Interv Cardiol. 2016 Apr;29(2):197-207. doi: 10.1111/joic.12270. Epub 2016 Jan 29.
To describe the significance of aortic root distortion (AD) and/or aortic valve insufficiency (AI) during balloon angioplasty of the right ventricular outflow tract (RVOT) performed to rule out coronary artery compression prior to transcatheter pulmonary valve (TPV) implantation.
AD/AI was assessed by retrospective review of all procedural aortographies performed to evaluate coronary anatomy prior to TPV implantation. AD/AI was also reviewed in all pre-post MPV implant echocardiograms to assess for progression.
From 04/2007 to 3/2015, 118 pts underwent catheterization with intent for TPV implant. Mean age and weight were 24.5 ± 12 years and 64.3 ± 20 kg, respectively. Diagnoses were: TOF (53%), D-TGA/DORV (18%), s/p Ross (15%), and Truncus (9%). Types of RV-PA connections were: conduits (96), bioprosthetic valves (14), and other (7). Successful TPV implant occurred in 91 pts (77%). RVOT balloon angioplasty was performed in 43/118 pts (36%). Aortography was performed in 18/43 pts with AD/AI noted in 6/18 (33%); 2 with D-TGA (1 s/p Lecompte, 1 s/p Rastelli), 2 with TOF, 1 Truncus and 1 s/p Ross. Procedure was aborted in the 2 who developed severe AD/AI. TPV was implanted in 3/4 patients with mild AD/AI. Review of pre-post TPV implantation echocardiograms in 83/91 pts (91%) revealed no new/worsened AI in any patient.
AD/AI is relatively common on aortography during simultaneous RVOT balloon angioplasty. Lack of AI progression by echocardiography post-TPV implant suggests these may be benign findings in most cases. However, AD/AI should be carefully evaluated in certain anatomic subtypes with close RVOT/aortic alignments.
描述在经导管肺动脉瓣(TPV)植入术前为排除冠状动脉受压而进行的右心室流出道(RVOT)球囊血管成形术期间主动脉根部扭曲(AD)和/或主动脉瓣关闭不全(AI)的意义。
通过回顾性分析TPV植入术前所有用于评估冠状动脉解剖结构的手术主动脉造影来评估AD/AI。还在所有MPV植入前后的超声心动图中评估AD/AI,以评估其进展情况。
2007年4月至2015年3月,118例患者接受了旨在植入TPV的导管插入术。平均年龄和体重分别为24.5±12岁和64.3±20千克。诊断包括:法洛四联症(TOF,53%)、大动脉转位/右心室双出口(D-TGA/DORV,18%)、Ross术后(s/p Ross,15%)和永存动脉干(9%)。RV-PA连接类型包括:人工血管(96例)、生物瓣膜(14例)和其他(7例)。91例患者(77%)成功植入TPV。43/118例患者(36%)进行了RVOT球囊血管成形术。18/43例患者进行了主动脉造影,其中6/18例(33%)发现AD/AI;2例为D-TGA(1例Lecompte术后,1例Rastelli术后),2例为TOF,1例永存动脉干和1例Ross术后。2例出现严重AD/AI的患者手术中止。3/4例轻度AD/AI患者植入了TPV。对83/91例患者(91%)的TPV植入前后超声心动图进行回顾发现,所有患者均未出现新的/加重的AI。
在同时进行RVOT球囊血管成形术期间,AD/AI在主动脉造影中相对常见。TPV植入术后超声心动图显示AI无进展,提示在大多数情况下这些可能是良性发现。然而,对于RVOT/主动脉排列紧密的某些解剖亚型,应仔细评估AD/AI。