Harun S R, Saleh E K, Gandahusada S, Hamdani C
Paediatr Indones. 1989 Jul-Aug;29(7-8):151-9.
A case congenital toxoplasmosis in a 15-day old infant was reported, citing the difficulties encountered in establishing the diagnosis due to the wide range of the disease's clinical spectrum. Congenital toxoplasmosis was suspected after finding hydrocephalus, cerebral calcification, and chorioretinitis. Serology tests with the ELISA technique were highly positive for antibodies against IgG, whereas anti-IgM was negative. The patient died before the second serological analysis was done. The final diagnosis of congenital toxoplasmosis was eventually established at autopsy, based on the detection of T. gondii in the brain, testicular, liver, spleen and striated muscle tissues.
报告了一例15日龄婴儿先天性弓形虫病病例,指出由于该疾病临床谱广泛,在确立诊断时遇到困难。发现脑积水、脑钙化和脉络膜视网膜炎后怀疑为先天性弓形虫病。采用ELISA技术进行的血清学检测显示,抗IgG抗体呈强阳性,而抗IgM为阴性。患者在进行第二次血清学分析前死亡。最终在尸检时根据在脑、睾丸、肝、脾和横纹肌组织中检测到弓形虫而确立了先天性弓形虫病的最终诊断。