阿达木单抗有效治疗心脏结节病的氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描证据
FDG PET/CT Evidence of Effective Treatment of Cardiac Sarcoidosis With Adalimumab.
作者信息
Miller Christina T, Sweiss Nadera J, Lu Yang
机构信息
From the Departments of *Radiology and †Medicine, University of Illinois Hospital & Health Sciences System, Chicago, IL.
出版信息
Clin Nucl Med. 2016 May;41(5):417-8. doi: 10.1097/RLU.0000000000001124.
A 53-year-old man with mediastinal lymph node biopsy and cardiac MRI-proven cardiac sarcoidosis (CS) received treatment with pacemaker and steroids. FDG PET/CT showed active CS despite treatment with prednisone and methotrexate. Addition of weekly adalimumab (Humira) injections was introduced for 3 months. Follow-up FDG PET/CT showed complete resolution of CS as well as improvement of other sarcoid lesions in the thoracic lymph nodes.
一名53岁男性，经纵隔淋巴结活检及心脏磁共振成像证实患有心脏结节病（CS），接受了起搏器和类固醇治疗。尽管使用了泼尼松和甲氨蝶呤，但氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET/CT）显示CS仍处于活动期。加用了每周一次的阿达木单抗（修美乐）注射，持续3个月。随访的FDG PET/CT显示CS完全消退，胸部淋巴结的其他结节病病变也有所改善。
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