Caproşu M, Stefănescu E, Petrovanu M, Radu C
Rev Med Chir Soc Med Nat Iasi. 1989 Apr-Jun;93(2):357-61.
Further studies in view of obtaining new stable phtalasiniuilides present the synthesis and physico-chemical and biological characterization of certain derivatives obtained through the action of p-phenyl-phenacyl and p-nitro-phenacyl bromides upon R-phtalasine. The structure of the new products was confirmed by physicochemical and spectral analyses. The preliminary biological tests showed a moderate antimicrobial activity of certain studies compounds.
为了获得新的稳定酞嗪酮类化合物而进行的进一步研究包括某些衍生物的合成、物理化学及生物学特性表征,这些衍生物是通过对苯苯基苯甲酰溴和对硝基苯甲酰溴作用于R-酞嗪而得到的。通过物理化学和光谱分析确定了新产品的结构。初步生物学测试表明某些研究化合物具有中等抗菌活性。