Bauermeister J, Giguere R, Dolezal C, Leu C S, Febo I, Cranston R D, Mayer K, McGowan I, Carballo-Diéguez A
University of Michigan School of Public Health, Center for Sexuality & Health Disparities (SexLab), Ann Arbor.
Columbia University and New York State Psychiatric Institute, HIV Center for Clinical and Behavioral Studies, New York.
AIDS Educ Prev. 2016 Feb;28(1):1-10. doi: 10.1521/aeap.2016.28.1.1.
We examined how experiences with a rectal placebo gel and applicator used with receptive anal intercourse (RAI) related to young men who have sex with men's (YMSM) likelihood of using a rectal microbicide gel and applicator in the future. An ethnically diverse sample of 95 YMSM (aged 18 to 30 years) were asked to insert hydroxyethylcellulose (HEC) placebo gel rectally before RAI during 12 weeks and report the product's acceptability (i.e., satisfaction with applicator and gel, respectively; perceived gel side effects; and sexual satisfaction when gel was used) and likelihood of future microbicide use. Main and interaction effects predicting future use intentions were tested using linear regression. We found a positive association between future use intentions and applicator satisfaction (b = .33, p < .001). In a subsequent interaction effects model, we found that greater gel satisfaction was associated with increased future use intentions; however, the strength of this relationship was magnified when YMSM reported greatest satisfaction with the rectal applicator. Applicator satisfaction may be a salient factor in YMSM's decision-making to use a rectal microbicide in the future. Although the importance of developing a satisfactory rectal microbicide gel for YMSM is undeniable for its future use, our results also emphasize the importance of developing strategies that increase YMSM's comfort and skill when using a rectal applicator. Future research examining how to optimize the design, properties, and characteristics of a rectal applicator as a strategy to promote greater satisfaction and use among YMSM is merited.
我们研究了与接受肛交（RAI）相关的直肠安慰剂凝胶和涂抹器的使用体验，与男男性行为者（YMSM）未来使用直肠杀菌剂凝胶和涂抹器可能性之间的关系。95名年龄在18至30岁之间、种族各异的YMSM被要求在12周内进行RAI之前经直肠插入羟乙基纤维素（HEC）安慰剂凝胶，并报告该产品的可接受性（即分别对涂抹器和凝胶的满意度；感知到的凝胶副作用；以及使用凝胶时的性满意度）和未来使用杀菌剂的可能性。使用线性回归测试预测未来使用意图的主要和交互作用。我们发现未来使用意图与涂抹器满意度之间存在正相关（b = 0.33，p < 0.001）。在随后的交互作用模型中，我们发现更高的凝胶满意度与增加的未来使用意图相关；然而，当YMSM报告对直肠涂抹器的满意度最高时，这种关系的强度会放大。涂抹器满意度可能是YMSM未来决定使用直肠杀菌剂的一个显著因素。尽管为YMSM开发令人满意的直肠杀菌剂凝胶对其未来使用的重要性不可否认，但我们的结果也强调了制定策略以提高YMSM使用直肠涂抹器时的舒适度和技能的重要性。值得进行未来研究，探讨如何优化直肠涂抹器的设计、特性和特点，作为提高YMSM满意度和使用率的一种策略。
