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阻塞性睡眠呼吸暂停患者接受减重手术后对术后心肺并发症的担忧是否合理?一项系统评价。

Is fear for postoperative cardiopulmonary complications after bariatric surgery in patients with obstructive sleep apnea justified? A systematic review.

作者信息

de Raaff Christel A L, Coblijn Usha K, de Vries Nico, van Wagensveld Bart A

机构信息

Department of Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, the Netherlands.

Department of Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, the Netherlands.

出版信息

Am J Surg. 2016 Apr;211(4):793-801. doi: 10.1016/j.amjsurg.2015.10.026. Epub 2016 Jan 5.

Abstract

BACKGROUND

To evaluate the influence of obstructive sleep apnea (OSA) on postoperative cardiopulmonary complications in bariatric surgery patients.

METHODS

PubMed, Embase, and the Cochrane central register databases were searched. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was used for reviewing.

RESULTS

Thirteen studies were included (n = 98,935). OSA was documented in 36,368 (37%) patients. The cardiopulmonary complication rate varied between .0% and 25.8%; no clear association with OSA was found (rate .0% to 18%), possibly because of optimized situations such as continuous positive airway pressure. OSA appeared to be no independent risk factor for intensive care unit (ICU) admission, death, or longer length of stay in most studies.

CONCLUSIONS

Overall, presented data showed no clear association of OSA with cardiopulmonary morbidity, ICU admissions, mortality, and length of stay after bariatric surgery. Although this questions the justification of admitting OSA patients to the ICU, future studies are required investigating the effect of monitoring strategies and optimizing treatments including continuous positive airway pressure use.

摘要

背景

评估阻塞性睡眠呼吸暂停(OSA)对肥胖症手术患者术后心肺并发症的影响。

方法

检索了PubMed、Embase和Cochrane中心注册数据库。采用系统评价和Meta分析的首选报告项目声明进行综述。

结果

纳入13项研究(n = 98935)。36368例(37%)患者记录有OSA。心肺并发症发生率在0.0%至25.8%之间;未发现与OSA有明确关联(发生率0.0%至18%),可能是由于持续气道正压通气等优化情况。在大多数研究中,OSA似乎不是重症监护病房(ICU)入住、死亡或住院时间延长的独立危险因素。

结论

总体而言,现有数据显示OSA与肥胖症手术后的心肺发病率、ICU入住、死亡率和住院时间无明确关联。尽管这对将OSA患者收入ICU的合理性提出了质疑,但仍需要未来的研究来调查监测策略的效果以及优化包括持续气道正压通气使用在内的治疗方法。

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