Fields Emma C, Weiss Elisabeth
Virginia Commonwealth University, Richmond, VA, USA.
Radiat Oncol. 2016 Feb 2;11:15. doi: 10.1186/s13014-016-0591-0.
Cervical cancer is a leading cause of mortality in women worldwide. Staging and management of cervical cancer has for many years been based on clinical exam and basic imaging such as intravenous pyelogram and x-ray. Unfortunately, despite advances in radiotherapy and the inclusion of chemotherapy in the standard plan for locally advanced disease, local control has been unsatisfactory. This situation has changed only recently with the increasing implementation of magnetic resonance image (MRI)-guided brachytherapy. The purpose of this article is therefore to provide an overview of the benefits of MRI in the evaluation and management of cervical cancer for both external beam radiotherapy and brachytherapy and to provide a practical approach if access to MRI is limited.
宫颈癌是全球女性死亡的主要原因。多年来,宫颈癌的分期和治疗一直基于临床检查以及静脉肾盂造影和X线等基础影像学检查。不幸的是,尽管放射治疗取得了进展,且局部晚期疾病的标准治疗方案中纳入了化疗,但局部控制效果仍不尽人意。这种情况直到最近随着磁共振成像(MRI)引导下近距离放疗的日益普及才有所改变。因此,本文旨在概述MRI在宫颈癌外照射放疗和近距离放疗的评估与治疗中的益处,并在MRI设备有限的情况下提供一种实用的方法。