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[中国3个城市男男性行为HIV感染者艾滋病相关随访干预及抗病毒治疗覆盖情况及其相关性]

[Coverage of HIV related follow-up intervention and antiretroviral treatment and its correlation among HIV-positive men who have sex with men of 3 cities in China].

作者信息

Hu Xiaosong, Chen Fang, Ding Fan, Lin Xiaojie, Wang Xiaodong, He Huan, Huang Wen, Yang Qiaohong, Zhang Hongbo

机构信息

School of Public Health, Anhui Medical University, Hefei 230032, China.

Email:

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2015 Nov;49(11):945-9.

PMID:26833002
Abstract

OBJECTIVE

To understand the coverage of HIV related intervention and antiviral treatment among HIV-positive men who have sex with men (MSM) and to examine factors of initiating antiretroviral treatment.

METHODS

A total of 501 HIV-positive MSM were recruited by "snowballing" sampling in Chengdu (160), Chongqing (168) and Guangzhou (173) from January to June, 2013. Participants who were older than18 years, had sex with men, HIV-infected, were living in these 3 cities when survey was conducted were eligible for subjects of this survey. The data were collected by computer assisted survey, including social demography, the coverage of HIV related follow-up intervention and ART, related knowledge level, sexual behaviors in the last 6 months, as well as notification to sexual partners and family. We analyzed the influence factors for initiating ART by Multiple Unconditioned Logistic Regression.

RESULTS

Among 501 HIV-positive MSM, the ratio of CD4 counting and HIV viral load testing were 90.8% (455) and 19.4% (97), respectively. The percentage of the latest CD4 counting not more than 350 per µl was 33.0% (150/455). The coverage of initiated ART among the participants who met the qualification was 56.0% (84/150). The multivariable Logistic regression analysis showed that the possibility of not on ART among participants who were migrants increased to 5.21(2.33-11.66) times of the local residents and the possibility among participants who were diagnosed STD in the last year increased to 2.70(1.12-6.55) times of those who were not infected STD, the possibility of not on ART among participants who had sex with male occasional or commercial partner in the last 6 months increased to 2.16(1.03-4.50) times of those who hadn't, and the possibility among participants who had anal sex with condom use in the past 6 months increased to 2.68(1.10-6.50) times of those who couldn't insist using condom.

CONCLUSION

There were low coverage of series of HIV/AIDS related intervention services among HIV-positive MSM in Chengdu, Chongqi and Guangzhou. Migrants, had sex with male occasional or commercial partner, had anal sex with condom use in the past 6 months, not infected STD in the last year may be the independent risk factors for HIV-positive MSM to not initiating ART.

摘要

目的

了解男男性行为者(MSM)艾滋病病毒感染者中艾滋病相关干预措施及抗病毒治疗的覆盖情况,并探讨开始抗逆转录病毒治疗的影响因素。

方法

2013年1月至6月,通过“滚雪球”抽样方法,在成都(160例)、重庆(168例)和广州(173例)共招募了501例MSM艾滋病病毒感染者。纳入标准为年龄大于18岁、与男性发生过性行为、感染艾滋病病毒且调查时居住在这3个城市。采用计算机辅助调查收集数据,内容包括社会人口学信息、艾滋病相关随访干预及抗病毒治疗的覆盖情况、相关知识水平、近6个月的性行为情况以及向性伴和家人告知情况。采用多因素非条件Logistic回归分析开始抗病毒治疗的影响因素。

结果

501例MSM艾滋病病毒感染者中,CD4细胞计数检测率和艾滋病病毒载量检测率分别为90.8%(455例)和19.4%(97例)。最近一次CD4细胞计数每微升不超过350个的比例为33.0%(150/455)。符合治疗条件者中开始抗病毒治疗的比例为56.0%(84/150)。多因素Logistic回归分析显示,外地户籍者未接受抗病毒治疗的可能性是本地户籍者的5.21(2.33 - 11.66)倍,近1年有性传播疾病诊断史者未接受抗病毒治疗的可能性是无感染史者的2.70(1.12 - 6.55)倍,近6个月与男性临时性伴或商业性伴发生过性行为者未接受抗病毒治疗的可能性是未发生过此类行为者的2.16(1.03 - 4.50)倍,近6个月有使用避孕套肛交行为者未接受抗病毒治疗的可能性是不能坚持使用避孕套者的2.68(1.10 - 6.50)倍。

结论

成都、重庆和广州的MSM艾滋病病毒感染者中艾滋病相关系列干预服务覆盖水平较低。外地户籍、近6个月与男性临时性伴或商业性伴发生过性行为、近6个月有使用避孕套肛交行为、近1年无感染性传播疾病史可能是MSM艾滋病病毒感染者未开始抗病毒治疗的独立危险因素。

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