Calabrò Emanuele, Magazù Salvatore
Department of Physics and Earth Sciences, University of Messina, Messina, Italy.
Bioelectromagnetics. 2016 Feb;37(2):99-107. doi: 10.1002/bem.21956. Epub 2016 Feb 2.
Effects of exposure of 4 h to mobile phones microwaves at 1765 MHz at a power density around 940 mW/m(2) on four typical proteins (hemoglobin in H2 O solution, and myoglobin, bovine serum albumin, and lysozyme in D2 O solution) were studied by means of Fourier Transform Infrared spectroscopy and Fourier self-deconvolution analysis. Increase in intensity of parallel β-sheet component around 1635 cm(-1) was observed after exposure of hemoglobin, myoglobin, and bovine serum albumin, showing that a mechanism of unfolding occurred after exposure, whereas no appreciable change in the amide I region occurred after lysozyme exposure. In addition, a relationship between protein dipole moment and protein unfolding rate was demonstrated with a correlation coefficient r = 0.973 and 95% confidence interval.
通过傅里叶变换红外光谱和傅里叶自去卷积分析，研究了在功率密度约为940 mW/m²、频率为1765 MHz的条件下，暴露于手机微波4小时对四种典型蛋白质（H₂O溶液中的血红蛋白、D₂O溶液中的肌红蛋白、牛血清白蛋白和溶菌酶）的影响。暴露后，观察到血红蛋白、肌红蛋白和牛血清白蛋白在1635 cm⁻¹左右的平行β-折叠成分强度增加，表明暴露后发生了蛋白质展开机制，而溶菌酶暴露后酰胺I区域没有明显变化。此外，还证明了蛋白质偶极矩与蛋白质展开速率之间的关系，相关系数r = 0.973，置信区间为95%。
