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慢性自发性荨麻疹(CSU):加拿大皮肤科医生的观点。

Chronic Spontaneous Urticaria (CSU): Canadian Dermatologists' Perspective.

作者信息

Cheung Loretta Y, Lynde Charles W

机构信息

Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.

Department of Medicine, University of Toronto, Toronto, ON, Canada

出版信息

J Cutan Med Surg. 2016 Jul;20(4):308-12. doi: 10.1177/1203475416631521. Epub 2016 Feb 1.

Abstract

BACKGROUND

Chronic spontaneous urticaria (CSU) is a skin disorder that is said to be "frustrating" and "difficult to treat." It is characterized by recurrent hives for more than 6 weeks, and is further divided into spontaneous or inducible by physical stimuli.(1) To better understand dermatologists' perspective of this disorder, a survey was conducted with Canadian dermatologists.

METHODS

A detailed online practice survey was sent to all currently practicing Canadian dermatologists.

RESULTS

In all, 80 responses were received (response rate of 20%). Most respondents in Canada had treated patients with CSU (98.4%), with many of the patients having the disease last over 6 months (86.6%). A majority of the patients were female, with 84.1% of the respondents having over 50% of their patients as female. Most patients were over the age of 30 (74.2%). Of dermatologists, 85.7% felt that investigations were unhelpful in diagnosing CSU in a patient. Of respondents, 37.1% were not satisfied with current treatment methods of CSU, and 43.6% somewhat satisfied. Popular therapies included H1 and H2 antihistamines, oral corticosteroids, and montelukast. There were 16.1% of dermatologists who had over 50% of their patients refractory to treatment.

CONCLUSIONS

There was a clear demographic preponderance for CSU patients with a majority as female over age 30. Investigations ordered for CSU patients do not seem to be helpful among dermatologists. Satisfaction with current therapies and investigations was quite low among Canadian dermatologists, suggesting new therapies are indicated.

摘要

背景

慢性自发性荨麻疹(CSU)是一种皮肤疾病,被认为“令人沮丧”且“难以治疗”。其特征为荨麻疹反复发作超过6周,并进一步分为自发性或由物理刺激诱发。(1)为了更好地了解皮肤科医生对这种疾病的看法,对加拿大皮肤科医生进行了一项调查。

方法

向所有目前执业的加拿大皮肤科医生发送了一份详细的在线执业调查问卷。

结果

共收到80份回复(回复率为20%)。加拿大的大多数受访者都曾治疗过CSU患者(98.4%),其中许多患者患病时间超过6个月(86.6%)。大多数患者为女性,84.1%的受访者表示其患者中超过50%为女性。大多数患者年龄超过30岁(74.2%)。85.7%的皮肤科医生认为检查对诊断CSU患者并无帮助。37.1%的受访者对CSU目前的治疗方法不满意,43.6%的受访者 somewhat satisfied(此处原文有误,推测可能是“ somewhat satisfied”,可译为“ somewhat satisfied”)。常用治疗方法包括H1和H2抗组胺药、口服糖皮质激素和孟鲁司特。16.1%的皮肤科医生表示其超过50%的患者治疗无效。

结论

CSU患者在人口统计学上存在明显的优势,大多数为30岁以上的女性。皮肤科医生似乎认为为CSU患者进行的检查并无帮助。加拿大皮肤科医生对目前的治疗方法和检查的满意度相当低,这表明需要新的治疗方法。

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