Shi Yunzhou, Hou Tinghui, Zheng Qianhua, Liu Ying, Yang Ting, Li Ying
Department of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine, Jinniu District, Chengdu, Sichuan, China.
Medicine (Baltimore). 2019 Jun;98(24):e16036. doi: 10.1097/MD.0000000000016036.
The purpose of this paper is to evaluate the effectiveness and safety of acupoint catgut embedding in the treatment of chronic urticaria (CU).
We will electronically search PubMed, Medline, Embase, Web of Science, the Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, and Wan-Fang Database from their inception to March 2019. In addition, we will manually retrieve other resources including the reference lists of identified publications, conference articles, and gray literature. The clinical randomized controlled trials or quasi-randomized controlled trials related to acupoint catgut embedding for the treatment of CU will be included in the study. The language is limited to Chinese and English. Research selection, data extraction, and research quality assessment will be independently completed by 2 researchers. Data were synthesized by using a fixed effect model or random effect model depend on the heterogeneity test. The total effective rate was the primary outcomes. Skin disease quality of life index scores, adverse events, and recurrence rates will also be assessed as secondary outcomes. RevMan V.5.3 statistical software will be used for meta-analysis. If it is not appropriate for a meta-analysis, then a descriptive analysis will be conducted. Data synthesis will use the risk ratio and the standardized or weighted average difference of continuous data to represent the results.
This study will provide a high-quality synthesis to assess the effectiveness and safety of acupoint catgut embedding for patients with CU.
This systematic review will provide evidence to judge whether acupoint catgut embedding is an effective intervention for patients with CU.
PROSPERO, CRD42019129459.
本文旨在评估穴位埋线治疗慢性荨麻疹（CU）的有效性和安全性。
我们将通过电子检索从创刊至2019年3月的PubMed、Medline、Embase、Web of Science、Cochrane对照试验中心注册库、中国知网、中国生物医学文献数据库、中国科学期刊数据库和万方数据库。此外，我们还将人工检索其他资源，包括已识别出版物的参考文献列表、会议文章和灰色文献。纳入与穴位埋线治疗CU相关的临床随机对照试验或半随机对照试验。语言限于中文和英文。研究筛选、数据提取和研究质量评估将由2名研究人员独立完成。根据异质性检验，使用固定效应模型或随机效应模型对数据进行合成。总有效率为主要结局。皮肤病生活质量指数评分、不良事件和复发率也将作为次要结局进行评估。将使用RevMan V.5.3统计软件进行荟萃分析。如果不适合进行荟萃分析，则进行描述性分析。数据合成将使用风险比和连续数据的标准化或加权平均差来表示结果。
本研究将提供高质量的综合分析，以评估穴位埋线对CU患者的有效性和安全性。
本系统评价将为判断穴位埋线是否为CU患者的有效干预措施提供证据。
PROSPERO，CRD42019129459。
Zotero 插件