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模仿转移性副神经节瘤的轴位浆细胞瘤:经后路环形重建

Plasmacytoma to the Axis Mimicking Metastatic Paraganglioma: Circumferential Reconstruction via Posterior Approach.

作者信息

Park Young-Seop, Hyun Seung-Jae, Kim Ki-Jeong, Jahng Tae-Ahn

机构信息

Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Gyeonggi, Korea.

出版信息

Korean J Spine. 2015 Dec;12(4):283-6. doi: 10.14245/kjs.2015.12.4.283. Epub 2015 Dec 31.

DOI:10.14245/kjs.2015.12.4.283
PMID:26834819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4731566/
Abstract

Plasmacytoma is a malignant plasma cell tumor growing within soft tissue or the axial skeleton. Here, we present the case of a patient with plasmacytoma of the axis vertebra who underwent decompressive surgery with reconstruction via a posterior approach. The patient was referred because of quadriparesis with severe neck pain. Magnetic resonance imaging revealed a relatively demarcated, highly enhanced mass lesion in a destructed axis, with spinal cord compression. Computed tomography revealed a 5.6×4.3 cm adrenal mass at the left retroperitoneal space. We suspected the axis lesion to be a metastatic paraganglioma from the adrenal mass. The patient underwent total excision of the tumor under an operative microscope with occipitocervical fixation. Histopathologically, the tumor was shown to be a plasmacytoma. Following the operation, the patient recovered without significant complications. This was a rare case of plasmacytoma in the axis, mimicking metastatic paraganglioma.

摘要

浆细胞瘤是一种生长于软组织或中轴骨骼的恶性浆细胞肿瘤。在此,我们报告一例枢椎浆细胞瘤患者,该患者接受了后路减压手术并进行了重建。患者因四肢瘫伴严重颈部疼痛前来就诊。磁共振成像显示在破坏的枢椎中有一个边界相对清晰、高度强化的肿块病变,伴有脊髓受压。计算机断层扫描显示左腹膜后间隙有一个5.6×4.3 cm的肾上腺肿块。我们怀疑枢椎病变是肾上腺肿块转移而来的副神经节瘤。患者在手术显微镜下接受了肿瘤全切并进行了枕颈固定。组织病理学检查显示肿瘤为浆细胞瘤。术后患者恢复良好,无明显并发症。这是一例罕见的枢椎浆细胞瘤病例,误诊为转移性副神经节瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/f6b6c96a4d2f/kjs-12-283-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/75a049eb1623/kjs-12-283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/173fe87c83a0/kjs-12-283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/b82161c1c3cc/kjs-12-283-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/f6b6c96a4d2f/kjs-12-283-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/75a049eb1623/kjs-12-283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/173fe87c83a0/kjs-12-283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/b82161c1c3cc/kjs-12-283-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d58/4731566/f6b6c96a4d2f/kjs-12-283-g004.jpg

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本文引用的文献

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Extramedullary plasmacytoma are characterized by a 'myeloma-like' immunophenotype and genotype and occult bone marrow involvement.髓外浆细胞瘤的特征是具有“骨髓瘤样”免疫表型和基因型以及隐匿性骨髓受累。
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Outcomes and patterns of failure in solitary plasmacytoma: a multicenter Rare Cancer Network study of 258 patients.
孤立性浆细胞瘤的预后与失败模式:一项针对258例患者的多中心罕见癌症网络研究
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