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支架置入术或冠状动脉搭桥术后重返工作岗位及生活质量的倾向匹配比较。

A propensity matched comparison of return to work and quality of life after stenting or coronary artery bypass surgery.

作者信息

Maznyczka Annette M, Howard James P, Banning Amerjeet S, Gershlick Anthony H

机构信息

Kings College London, London, UK; Department of Medical Sciences, University College London, London, UK.

International Centre for Circulatory Health, National Heart and Lung Institute , London , UK.

出版信息

Open Heart. 2016 Jan 13;3(1):e000322. doi: 10.1136/openhrt-2015-000322. eCollection 2016.

Abstract

OBJECTIVES

We sought to determine (1) return to work (RTW) rates, (2) long-term employment (>12 months postprocedure), (3) time taken to RTW, and (4) quality of life (QoL), in patients treated with percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).

METHODS

Questionnaires regarding RTW were sent to 689 PCI and 169 CABG patients who underwent PCI or CABG at University Hospitals of Leicester Trust, UK, from May 2012 to May 2013. QoL was also measured using the European QoL 5-dimensions questionnaire (EQ-5D). Responses from patients employed preprocedure were analysed using multivariate logistic regression. Propensity score-matching was further used to compare similar patient populations receiving PCI or CABG.

RESULTS

The response rate was 38% (235 PCI and 88 CABG patients). 241 respondents (75%) were employed preprocedure. Of these 162 (93%) PCI and 51 (77%) CABG patients returned to work, whereas 147 (85%) PCI and 41 (62%) CABG patients were still employed at >12 months postprocedure. After propensity analysis, there was no significant difference between PCI and CABG patients in RTW, long-term employment, nor QoL. The median time taken to RTW was 6 weeks after PCI and 13 weeks after CABG (p=0.001). The effect remained significant after multivariate analysis (p=0.001) and propensity analysis (p=0.001).

CONCLUSIONS

In this first propensity score-matched study comparing RTW and QoL after PCI or CABG strict propensity matching indicates that RTW or QoL, is similar for PCI or CABG, albeit the number of matched pairs was small. There are differences, however, in delay in RTW.

摘要

目的

我们试图确定接受经皮冠状动脉介入治疗(PCI)或冠状动脉旁路移植术(CABG)的患者的(1)重返工作岗位(RTW)率、(2)长期就业情况(术后超过12个月)、(3)重返工作岗位所需时间,以及(4)生活质量(QoL)。

方法

向2012年5月至2013年5月在英国莱斯特大学医院信托基金接受PCI或CABG治疗的689例PCI患者和169例CABG患者发送了关于RTW的调查问卷。还使用欧洲五维生活质量问卷(EQ-5D)对生活质量进行了测量。对术前受雇患者的回复进行多因素逻辑回归分析。进一步使用倾向得分匹配法比较接受PCI或CABG的相似患者群体。

结果

回复率为38%(235例PCI患者和88例CABG患者)。241名受访者(75%)术前受雇。其中,162例(93%)PCI患者和51例(77%)CABG患者重返工作岗位,而147例(85%)PCI患者和41例(62%)CABG患者在术后超过12个月仍受雇。经过倾向分析,PCI患者和CABG患者在RTW、长期就业或生活质量方面没有显著差异。PCI术后重返工作岗位的中位时间为6周,CABG术后为13周(p=0.001)。多因素分析(p=0.001)和倾向分析(p=0.001)后,该效应仍然显著。

结论

在这项首次进行的倾向得分匹配研究中,比较PCI或CABG术后的RTW和生活质量,严格的倾向匹配表明,PCI或CABG的RTW或生活质量相似,尽管匹配对的数量较少。然而,在重返工作岗位的延迟方面存在差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88b/4716452/fc192222722c/openhrt2015000322f01.jpg

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