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[纤连蛋白在链球菌黏附过程中的作用]

[The role of fibronectin in the streptococcal adhesion process].

作者信息

Lyzlova L V, Voĭtsekhovskiĭ B L, Grabovskaia K B, Totolian A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1989 Jul(7):7-12.

PMID:2683526
Abstract

The work shows that fibronectin obtained from human plasma is capable of binding with streptococci of different groups with almost equal effectiveness. Fibronectin bound to bacterial cells inhibits the adhesion of group A streptococci onto vaginal cells, but it produces no effect on the adhesion of group B streptococci. The binding constant of fibronectin 125I is equal to 10(6) -M-1, which indicates that the level of the specificity of interaction is not sufficiently high.

摘要

该研究表明,从人血浆中获得的纤连蛋白能够以几乎相同的效力与不同组的链球菌结合。与细菌细胞结合的纤连蛋白可抑制A组链球菌对阴道细胞的黏附,但对B组链球菌的黏附没有影响。纤连蛋白125I的结合常数等于10(6) -M-1,这表明相互作用的特异性水平不够高。

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