Borgies P, Ferrant A, Michaux J L
Acta Clin Belg. 1989;44(3):182-8. doi: 10.1080/17843286.1989.11718011.
Seven cases of granulocytic sarcoma (GS) with different clinical presentations are reported. Granulocytic sarcoma is diagnosed by tumor biopsy. The antilysozyme immunoperoxidase technique and the ASD chloroacetate esterase staining are used to confirm the diagnosis. The recent development of immunohistological staining, for demonstration of intra-cellular or surface antigens, is also useful to recognize GS. The prognostic significance of GS is discussed. For isolated GS, early aggressive treatment with chemotherapy and local radiotherapy is proposed.
报告了7例具有不同临床表现的粒细胞肉瘤(GS)。粒细胞肉瘤通过肿瘤活检确诊。采用抗溶菌酶免疫过氧化物酶技术和α-萘酚醋酸酯酶染色来确诊。免疫组织化学染色用于显示细胞内或表面抗原的最新进展,对识别粒细胞肉瘤也很有用。讨论了粒细胞肉瘤的预后意义。对于孤立性粒细胞肉瘤,建议早期积极进行化疗和局部放疗。