Schwieger I, Gamulin Z, Suter P M
Department of Anesthesiology and Surgical Intensive Care, University Hospital of Geneva, Switzerland.
Acta Anaesthesiol Scand. 1989 Oct;33(7):527-34. doi: 10.1111/j.1399-6576.1989.tb02960.x.
This review covers the physiological and clinical implications of lung function during anesthesia and respiratory insufficiency in the postoperative period. We have divided it into 3 main sections: 1) lung function changes induced by anesthesia and surgery, in which the impact on pulmonary mechanics, ventilation/perfusion changes and gas exchange are examined; 2) physiological implications of postoperative respiratory function secondary to decreased alveolar ventilation, development of atelectasis, and interstitial lung edema; and 3) clinical implications of postoperative respiratory failure. In this last section we analyze the current therapeutic modalities available to reduce the incidence of postoperative respiratory failure, as well as related morbidity and mortality.
本综述涵盖了麻醉期间肺功能的生理及临床意义以及术后呼吸功能不全。我们将其分为3个主要部分：1）麻醉和手术引起的肺功能变化，其中探讨了对肺力学、通气/灌注变化及气体交换的影响；2）肺泡通气减少、肺不张形成及间质性肺水肿继发的术后呼吸功能的生理意义；3）术后呼吸衰竭的临床意义。在最后这一部分，我们分析了目前可用于降低术后呼吸衰竭发生率以及相关发病率和死亡率的治疗方式。
