Mazarro Alejandro, de Pablo Alba, Puiggròs Carolina, Velasco M Mercedes, Saez Manel, Pamias Jorge, Bescós Coro
Oral and Maxillofacial Department, Hospital Vall d'Hebron, Barcelona, Spain.
Department of Nutrition, Hospital Vall d'Hebron, Barcelona, Spain.
Head Neck. 2016 Apr;38 Suppl 1:E2004-10. doi: 10.1002/hed.24369. Epub 2016 Feb 2.
The best treatment for advanced tongue tumors remains controversial. Total glossectomy with laryngeal preservation is considered a feasible option, despite its morbidity.
A retrospective analysis of 12 total glossectomies with laryngeal preservation was performed in order to assess the available reconstruction techniques and analyze survival and functional outcomes.
One-year overall survival (OS) and disease-free survival (DFS) rates were 58.3% and 33.3%, respectively, both dropping to 25% after 3 years. Permanent gastrostomy was necessary in 10 patients, although videofluoroscopy revealed adequate tolerance to liquids. Speech intelligibility was satisfactory in 50% of the patients and severely impaired in the remaining 50%.
Laryngeal preservation in the context of advanced tumors of the tongue without supraglottic invasion carried similar oncologic results to total glossectomy with laryngectomy, but offers a better phonatory function. However, it is usually associated with a higher gastrostomy dependency ratio. A scrupulous selection of candidates is mandatory. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2004-E2010, 2016.
晚期舌部肿瘤的最佳治疗方法仍存在争议。保留喉功能的全舌切除术虽有一定并发症,但被认为是一种可行的选择。
对12例保留喉功能的全舌切除术进行回顾性分析,以评估可用的重建技术,并分析生存和功能结果。
1年总生存率(OS)和无病生存率(DFS)分别为58.3%和33.3%,3年后均降至25%。10例患者需要永久性胃造口术,尽管视频透视显示对液体有足够的耐受性。50%的患者语音清晰度令人满意,其余50%严重受损。
在无声门上侵犯的晚期舌部肿瘤患者中保留喉功能,其肿瘤学结果与全舌切除加喉切除术相似,但具有更好的发声功能。然而,它通常与更高的胃造口依赖率相关。必须严格筛选合适的患者。©2016威利期刊公司。头颈外科38:E2004 - E2010,2016。