Gardiner Paul A, Mishra Gita D, Dobson Annette J
School of Public Health, The University of Queensland, Herston, Queensland, Australia; Mater Research Institute, The University of Queensland, South Brisbane, Queensland, Australia.
School of Public Health, The University of Queensland, Herston, Queensland, Australia.
J Am Med Dir Assoc. 2016 Apr 1;17(4):372.e1-3. doi: 10.1016/j.jamda.2015.12.090. Epub 2016 Feb 2.
To investigate whether distinct trajectories of frailty exist in older women and whether they are associated with measures of socioeconomic status (SES) across adulthood.
Participants were 7484 women born in 1921-1926 from the Australian Longitudinal Study on Women's Health who were surveyed every 3 years from 1999 to 2011. Frailty was measured at each survey using the FRAIL scale. Group-based trajectory modeling was used to assess patterns of frailty. Multinomial logistic regression was used to examine associations of trajectories with SES (level of education, occupation, and ability to manage on income) across adulthood.
Three trajectory groups were identified: low (19.5%), increasing (40.7%), and high (39.9%). Compared with women in the increasing frailty group, those who reported difficulty managing on their income in 1999 were less likely to be in the low frailty group (relative risk ratio 0.57, 95% confidence interval 0.39-0.84) and more likely to be in the high frailty group (relative risk ratio 2.65, 95% confidence interval 2.07-3.39), after adjusting for other SES variables, age, and social support. Occupation and education were not associated with trajectories of frailty.
Some women remain frailty free until age 85-90 years. The strongest impact on frailty is late-life SES.
调查老年女性中是否存在不同的衰弱轨迹,以及这些轨迹是否与成年期社会经济地位(SES)指标相关。
参与者为7484名出生于1921 - 1926年的女性,来自澳大利亚女性健康纵向研究,她们在1999年至2011年期间每3年接受一次调查。每次调查时使用FRAIL量表测量衰弱情况。采用基于群体的轨迹模型评估衰弱模式。使用多项逻辑回归分析成年期衰弱轨迹与SES(教育水平、职业和收入管理能力)之间的关联。
确定了三个轨迹组:低衰弱组(19.5%)、衰弱增加组(40.7%)和高衰弱组(39.9%)。与衰弱增加组的女性相比,在调整了其他SES变量、年龄和社会支持因素后,那些在1999年报告收入管理困难的女性,进入低衰弱组的可能性较小(相对风险比0.57,95%置信区间0.39 - 0.84),而进入高衰弱组的可能性较大(相对风险比2.65,95%置信区间2.07 - 3.39)。职业和教育与衰弱轨迹无关。
一些女性直到85 - 90岁都没有衰弱问题。对衰弱影响最大的是晚年的社会经济地位。