Henchoz Yves, Fustinoni Sarah, Seematter-Bagnoud Laurence, Avendano Mauricio
Department of Epidemiology and Health Systems, Unisanté, University Centre for Primary Care and Public Health, Lausanne, Switzerland.
Service of Geriatric Medicine and Geriatric Rehabilitation, Lausanne University Hospital, Lausanne, Switzerland.
Int J Public Health. 2025 Jun 9;70:1608102. doi: 10.3389/ijph.2025.1608102. eCollection 2025.
This study examines how different measures of socioeconomic status (SES) across childhood and adulthood relate to frailty in older age.
Data came from the Lausanne cohort 65+ (Lc65+), a population-based study of approximately 4,500 older adults followed over 20 years. SES measures included education in young adulthood, occupational class in midlife, and specific early old-age factors: perceived income, wealth, financial strain, and receipt of financial subsidies. Frailty trajectories over a 10-year period were assessed using Fried's frailty phenotype and group-based trajectory modeling. Logistic regression models adjusted for sex, age, cohort, living situation, marital status, and number of children.
Lower education, occupational class, financial strain, and financial subsidies in older age were each independently associated with higher frailty risk at ages 65-70. Financial strain and financial subsidies in early old age increased odds of medium- (aOR, 1.48-1.69) and high-frailty (aOR, 2.07-2.28) trajectories.
SES across the life course strongly correlates with frailty in early old age. Early interventions and financial protection policies in older age could help mitigate frailty risk and SES-related frailty inequalities.
本研究探讨儿童期和成年期不同的社会经济地位(SES)衡量指标如何与老年期的衰弱相关。
数据来自洛桑65岁及以上队列研究(Lc65 +),这是一项对约4500名老年人进行了20年随访的基于人群的研究。SES衡量指标包括青年期教育程度、中年期职业阶层以及特定的老年早期因素:感知收入、财富、经济压力和获得的财政补贴。使用弗里德衰弱表型和基于群体的轨迹模型评估10年期间的衰弱轨迹。逻辑回归模型对性别、年龄、队列、生活状况、婚姻状况和子女数量进行了调整。
较低的教育程度、职业阶层、经济压力以及老年期的财政补贴均分别与65 - 70岁时较高的衰弱风险独立相关。老年早期的经济压力和财政补贴增加了中度(调整后比值比[aOR],1.48 - 1.69)和高度衰弱(aOR,2.07 - 2.28)轨迹的几率。
一生的社会经济地位与老年早期的衰弱密切相关。老年期的早期干预和财政保护政策有助于降低衰弱风险以及与社会经济地位相关的衰弱不平等。