Sica D A, Culpepper R M
Division of Nephrology, Medical College of Virginia, Richmond.
Am J Med Sci. 1989 Nov;298(5):331-3. doi: 10.1097/00000441-198911000-00011.
A male quadriplegic (C6--complete) with persistent chronic hyponatremia (serum sodium values ranging consistently from 117-132 mmol/L) developed acute hyponatremia with a serum sodium concentration of 98 mmol/L. This extreme hyponatremia related, in part, to a reversible defect in the excretion of a water load, while on a low (46 mmol/day) sodium diet. Subsequent ingestion of a normal sodium diet (150 mmol/day), with or without 0.1 mg of fludrocortisone (Florinef), reestablished his ability to excrete a water load normally. The etiology of this patient's hyponatremia is discussed as well as the unique concordance of factors which make hyponatremia a common occurrence among spinal-cord injured patients.
一名男性四肢瘫痪患者（C6完全性损伤），长期存在慢性低钠血症（血清钠值持续在117 - 132 mmol/L之间），其血清钠浓度降至98 mmol/L，出现了急性低钠血症。这种严重的低钠血症部分与低钠饮食（每天46 mmol）时水负荷排泄的可逆性缺陷有关。随后摄入正常钠饮食（每天150 mmol），无论是否服用0.1 mg氟氢可的松（Florinef），其排泄水负荷的能力均恢复正常。本文讨论了该患者低钠血症的病因，以及导致低钠血症在脊髓损伤患者中常见的各种因素的独特一致性。
