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[尼莫地平和脑血管循环。关于4例蛛网膜下腔出血的初步结果]

[Nimodipine and cerebrovascular circulation. Initial results apropos of 4 cases of subarachnoid hemorrhage].

作者信息

Texier J J, Lepetit J M, Moreau J J, Ravon R, Feiss P

出版信息

Agressologie. 1989 Jun;30(7):416-24.

PMID:2683822
Abstract

Nimodipine was included in the treatment of four patients who had previously presented subarachnoid hemorrhage; cerebral circulation has been assayed by means of "Tomophygmographie cérébrale ultra-sonore". In all four patients, use of Nimodipine has led to an improvement of cerebral circulation and then of the neurological status. Nimodipine is characterized by its very low therapeutic inertion. Data obtained both at the initiation and on interruption of the administration of this drug points to its original properties regarding cerebral circulation: indeed, the present observations suggest that Nimodipine behaves as a true vasoregulator.

摘要

尼莫地平被用于治疗4例曾患蛛网膜下腔出血的患者;采用“脑超声血流图”对脑循环进行了测定。在所有4例患者中,使用尼莫地平均使脑循环得到改善,进而使神经状态得到改善。尼莫地平的特点是治疗惰性极低。在开始和中断使用该药时获得的数据均表明其在脑循环方面具有独特性质:实际上,目前的观察结果表明尼莫地平是一种真正的血管调节剂。

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