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双侧支气管扩张作为支气管相关淋巴组织肺边缘区B细胞淋巴瘤的一种表现形式。

Bilateral Bronchiectasis as a Presentation Form of Pulmonary Marginal Zone B-Cell Lymphoma of Bronchus Associated Lymphoid Tissue.

作者信息

Ernst Glenda, Torres Carla, Borsini Eduardo, Vigovich Félix, Downey Daniel, Salvado Alajandro, Bosio Martín

机构信息

Hospital Británico de Buenos Aires, C1280AEB Buenos Aires, Argentina.

Hospital San Juan de Dios, Buenos Aires, Argentina.

出版信息

Case Rep Oncol Med. 2015;2015:975786. doi: 10.1155/2015/975786. Epub 2015 Dec 29.

Abstract

The pulmonary marginal zone B-cell lymphoma of bronchus associated lymphoid tissue of the lung (BALT) is a rare illness that can remain without symptoms. Radiological findings of pulmonary lymphoma are heterogeneous. In literature, bronchiectasis is only described in one patient who also had besides adenomegalies. We reported on a 48-year-old female patient. She showed symptoms consistent with dyspnea with productive cough; there were crepitant sounds in the auscultation. Pulmonary functional test has shown a severe restrictive pattern with a low FVC and DLCO. CT scan showed bronchiectasis in the medium lobule without adenomegalies. Echocardiogram was normal, and the laboratory findings only showed leukocytosis. There were no findings in the bronchoscopy, but the lung biopsy showed a B-cell pulmonary lymphoma (positive to CD20 and CD79a in immunostaining). A wide variety of radiological manifestations has been previously described; however, we have presented this rare case, with bronchiectasis, as unique radiological finding.

摘要

肺支气管相关淋巴组织(BALT)边缘区B细胞淋巴瘤是一种罕见疾病,可无症状。肺淋巴瘤的影像学表现多种多样。文献中仅描述了1例除淋巴结肿大外还伴有支气管扩张的患者。我们报告了1例48岁女性患者。她表现出与呼吸困难伴咳痰一致的症状;听诊时有捻发音。肺功能测试显示为严重限制性模式,FVC和DLCO降低。CT扫描显示中叶支气管扩张,无淋巴结肿大。超声心动图正常,实验室检查仅显示白细胞增多。支气管镜检查未发现异常,但肺活检显示为B细胞肺淋巴瘤(免疫染色CD20和CD79a阳性)。先前已描述了多种影像学表现;然而,我们呈现了这例伴有支气管扩张的罕见病例,作为独特的影像学发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bbe/4709615/078418fd5b9b/CRIONM2015-975786.001.jpg

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