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小鼠皮肤中的血清素和单胺氧化酶:接触香烟烟雾的影响。

Serotonin and monoamine oxidase in mouse skin: effects of cigarette smoke exposure.

作者信息

Essman W B

出版信息

J Med. 1977;8(2):95-101.

PMID:268400
Abstract

Mice were exposed to either air or cigarette smoke and the content and uptake of serotonin and activity of monoamine oxidase were determined. Serotonin concentration increased as a function of the frequency of exposure, while serotonin uptake by the skin was maximally increased after two 8 min. exposures. MAO activity for serotonin, but not for tyramine, was decreased by cigarette smoke exposure of more than 8 min.

摘要

将小鼠暴露于空气或香烟烟雾中,然后测定血清素的含量、摄取量以及单胺氧化酶的活性。血清素浓度随暴露频率增加而升高,而皮肤对血清素的摄取在两次8分钟暴露后达到最大增加。暴露于香烟烟雾超过8分钟会降低血清素而非酪胺的单胺氧化酶活性。

相似文献

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Serotonin and monoamine oxidase in mouse skin: effects of cigarette smoke exposure.小鼠皮肤中的血清素和单胺氧化酶:接触香烟烟雾的影响。
J Med. 1977;8(2):95-101.
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Irreversible inhibition of monoamine oxidase by some components of cigarette smoke.
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[Effect of protein denaturing reactions on retardation of the activity of rat liver mitochondrial monoamine oxidase by clorgyline and deprenyl].[蛋白质变性反应对氯吉兰和司来吉兰抑制大鼠肝线粒体单胺氧化酶活性的影响]
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Smoking related diseases: the central role of monoamine oxidase.与吸烟有关的疾病:单胺氧化酶的核心作用。
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Inhibition of human MAO-A and MAO-B by a compound isolated from flue-cured tobacco leaves and its neuroprotective properties in the MPTP mouse model of neurodegeneration.从烤烟叶片中分离出的一种化合物对人单胺氧化酶A和单胺氧化酶B的抑制作用及其在MPTP诱导的神经退行性变小鼠模型中的神经保护特性
Inflammopharmacology. 2003;11(2):183-8. doi: 10.1163/156856003765764353.
3
Studies on the interactions of tobacco leaf and tobacco smoke constituents and monoamine oxidase.
烟草叶片与烟草烟雾成分及单胺氧化酶相互作用的研究。
Neurotox Res. 2002 Mar;4(2):151-60. doi: 10.1080/10298420290015854.
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Pulmonary inactivation of 5-hydroxytryptamine is decreased during cigarette smoke ventilation of rat isolated lungs.在大鼠离体肺脏进行香烟烟雾通气期间,5-羟色胺的肺内失活减少。
Br J Pharmacol. 1982 Oct;77(2):245-8. doi: 10.1111/j.1476-5381.1982.tb09292.x.
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Effects of cigarette smoking on metabolic events in the lung.吸烟对肺部代谢事件的影响。
Environ Health Perspect. 1987 Jun;72:283-96. doi: 10.1289/ehp.8772283.