Essman W B
J Med. 1977;8(2):95-101.
Mice were exposed to either air or cigarette smoke and the content and uptake of serotonin and activity of monoamine oxidase were determined. Serotonin concentration increased as a function of the frequency of exposure, while serotonin uptake by the skin was maximally increased after two 8 min. exposures. MAO activity for serotonin, but not for tyramine, was decreased by cigarette smoke exposure of more than 8 min.
将小鼠暴露于空气或香烟烟雾中,然后测定血清素的含量、摄取量以及单胺氧化酶的活性。血清素浓度随暴露频率增加而升高,而皮肤对血清素的摄取在两次8分钟暴露后达到最大增加。暴露于香烟烟雾超过8分钟会降低血清素而非酪胺的单胺氧化酶活性。