Postovsky Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences , Ekaterinburg 620990, Russia.
Ural Federal University named after the First President of Russia, B.N. Yeltsin , Ekaterinburg 620002, Russia.
Org Lett. 2016 Feb 19;18(4):804-7. doi: 10.1021/acs.orglett.6b00081. Epub 2016 Feb 3.
A convenient approach to ladder-type 6H-benzo[4',5']thieno[2',3':4,5]thieno[3,2-b]indoles bearing various substituents in both terminal benzene rings has been developed. The protocol suggested for preparing these N,S-heteroacenes is based on using easily available reagents, such as cinnamic acids and arylhydrazines, which can be involved in the Fischer indole synthesis, as the key step. A similar condensed system of 12H-benzo[4″,5″]thieno[2″,3″:4',5']thieno[2',3':4,5]thieno[3,2-b]indole, bearing six rings, has also been obtained.
一种方便的方法被开发出来，用于合成具有各种取代基的 ladder-type 6H-benzo[4',5']thieno[2',3':4,5]thieno[3,2-b]indoles，这些取代基位于两个末端苯环上。用于制备这些 N,S-杂芳烃的方案基于使用容易获得的试剂，如肉桂酸和芳基肼，它们可以作为关键步骤参与 Fischer 吲哚合成。类似的 12H-benzo[4″,5″]thieno[2″,3″:4',5']thieno[2',3':4,5]thieno[3,2-b]indole 稠合体系，也含有六个环，也已经得到了。
