Saraux H, Lefrancois A
Klin Monbl Augenheilkd. 1977 Jun;170(6):818-20.
A patient with chronic granulocytic leukemia was treated with Busulfan for the three last months of pregnancy. The infant appeared normal except for an atypical tapetoretinal degeneration. We studied the other cases in the literature. All pregnancies produced an apparently normal infant although three infants were small. The case of Diamond had microphthalmia. We conclude that Busulfan is perhaps toxic to fetal retina.
一名慢性粒细胞白血病患者在妊娠最后三个月接受了白消安治疗。婴儿除了有非典型的视网膜色素变性外，看起来正常。我们研究了文献中的其他病例。尽管有三名婴儿体重较轻，但所有妊娠生出的婴儿表面上都正常。戴蒙德的病例有小眼畸形。我们得出结论，白消安可能对胎儿视网膜有毒性。
