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When the Fight against Fungi Goes Wrong.

作者信息

Wang Xiaowen, van de Veerdonk Frank L

机构信息

Department of Dermatology, Peking University First Hospital, Beijing, China.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboudumc, Nijmegen, The Netherlands.

出版信息

PLoS Pathog. 2016 Feb 4;12(2):e1005400. doi: 10.1371/journal.ppat.1005400. eCollection 2016 Feb.

DOI:10.1371/journal.ppat.1005400
PMID:26845151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4742062/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0472/4742062/50bb71b50528/ppat.1005400.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0472/4742062/50bb71b50528/ppat.1005400.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0472/4742062/50bb71b50528/ppat.1005400.g001.jpg

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J Exp Med. 2015 Sep 21;212(10):1641-62. doi: 10.1084/jem.20140280. Epub 2015 Aug 24.
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Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).功能获得性 STAT1 突变会损害慢性黏膜皮肤念珠菌病（CMC）患者的 STAT3 活性。
Eur J Immunol. 2015 Oct;45(10):2834-46. doi: 10.1002/eji.201445344. Epub 2015 Sep 1.
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IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations.
Mycopathologia. 2017 Feb;182(1-2):251-261. doi: 10.1007/s11046-016-0093-5. Epub 2016 Nov 23.
免疫缺陷。双等位基因RORC突变的人类对念珠菌和分枝杆菌的免疫受损。
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