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生命体征:美国 2011-2013 年酒精暴露的妊娠情况。

Vital Signs: Alcohol-Exposed Pregnancies--United States, 2011-2013.

机构信息

Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, CDC.

出版信息

MMWR Morb Mortal Wkly Rep. 2016 Feb 5;65(4):91-7. doi: 10.15585/mmwr.mm6504a6.

Abstract

BACKGROUND

Alcohol is a teratogen.* Prenatal alcohol exposure is associated with a range of adverse reproductive outcomes and can cause fetal alcohol spectrum disorders (FASDs) characterized by lifelong physical, behavioral, and intellectual disabilities. FASDs are completely preventable if a woman does not drink alcohol while pregnant.

METHODS

CDC analyzed data from the 2011-2013 National Survey of Family Growth to generate U.S. prevalence estimates of risk for an alcohol-exposed pregnancy for 4,303 nonpregnant, nonsterile women aged 15-44 years, by selected demographic and behavioral factors. A woman was considered at risk for an alcohol-exposed pregnancy during the past month if she had sex with a male, drank any alcohol, and did not (and her partner did not with her) use contraception in the past month; was not sterile; and had a partner (or partners) not known to be sterile.

RESULTS

The weighted prevalence of alcohol-exposed pregnancy risk among U.S. women aged 15-44 years was 7.3%. During a 1-month period, approximately 3.3 million women in the United States were at risk for an alcohol-exposed pregnancy.

CONCLUSIONS AND IMPLICATIONS FOR PUBLIC HEALTH PRACTICE

Alcohol use in pregnancy is associated with low birthweight, preterm birth, birth defects, and developmental disabilities. Women of reproductive age should be informed of the risks of alcohol use during pregnancy, and contraception should be recommended, as appropriate, for women who do not want to become pregnant. Women wanting a pregnancy should be advised to stop drinking at the same time contraception is discontinued. Health care providers should advise women not to drink at all if they are pregnant or there is any chance they might be pregnant. Alcohol misuse screening and behavioral counseling (also known as alcohol screening and brief intervention) is recommended for all adults in primary care, including reproductive-aged and pregnant women, as an evidenced-based approach to reducing alcohol consumption among persons who consume alcohol in excess of the recommended guidelines.

摘要

背景

酒精是一种致畸物。* 孕期饮酒会导致一系列不良生殖后果,并可能导致胎儿酒精谱系障碍(FASD),其特征为终生的身体、行为和智力残疾。如果女性在怀孕期间不饮酒,那么 FASD 是完全可以预防的。

方法

CDC 分析了 2011-2013 年全国生育调查的数据,根据选定的人口统计学和行为因素,为 4303 名年龄在 15-44 岁之间、未怀孕、未绝育的非怀孕女性生成了美国过去一个月内酒精暴露妊娠风险的流行率估计值。如果女性在过去一个月内与男性发生性行为、饮酒且未使用(且其伴侣未与她一起使用)避孕措施、未绝育且伴侣(或伴侣)未知绝育,则被认为存在过去一个月内酒精暴露妊娠风险。

结果

美国 15-44 岁女性中酒精暴露妊娠风险的加权流行率为 7.3%。在一个月期间,美国大约有 330 万女性存在酒精暴露妊娠风险。

结论和对公共卫生实践的意义

孕期饮酒与低出生体重、早产、出生缺陷和发育障碍有关。育龄女性应被告知孕期饮酒的风险,应酌情向不希望怀孕的女性推荐避孕措施。希望怀孕的女性应被告知在停止避孕的同时停止饮酒。如果女性怀孕或有可能怀孕,医疗保健提供者应建议其完全不饮酒。对于所有成年人,包括育龄和孕妇,包括在初级保健中,建议进行酒精滥用筛查和行为咨询(也称为酒精筛查和简短干预),作为减少过量饮酒者饮酒量的循证方法。

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