Avetisov S E, Bubnova I A, Antonov A A, Avetisov S E, Bubnova I A, Antonov A A
Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
Vestn Oftalmol. 2015 Sep-Oct;131(5):20-25. doi: 10.17116/oftalma2015131520-24.
Studying biomechanical properties of the fibrous tunic of the eye meets current clinical demands. Previous studies have proved bidirectional corneal applanation suitable for this purpose. The so called corneal elasticity coefficient is more informative in terms of corneal elastance than the two other parameters measured during bidirectional corneal applanation, namely, corneal resistance factor and corneal hysteresis. All three are known to have wide normal ranges. The aim of the present study was to determine the range of corneal resistance factor, corneal hysteresis, and corneal elasticity coefficient in a normal population.
This work summarizes data from 2205 patients (4410 eyes) with no ophthalmic pathology who got their ocular biomechanics examined with an Ocular Response Analyzer.
Normal ranges of biomechanical parameters of the fibrous tunic have been determined. Considerable variation has been demonstrated in central corneal thickness (from 448 to 685 µm, with the mean of 563 ± 37 µm). Moreover, the corneal resistance factor, corneal hysteresis, and corneal elasticity coefficient have been shown to have almost equal means and to decrease with age.
研究眼球纤维膜层的生物力学特性符合当前临床需求。先前的研究已证明双向角膜压平适用于此目的。就角膜弹性而言，所谓的角膜弹性系数比双向角膜压平过程中测量的其他两个参数（即角膜阻力因子和角膜滞后）更具信息量。已知这三个参数的正常范围都很宽。本研究的目的是确定正常人群中角膜阻力因子、角膜滞后和角膜弹性系数的范围。
这项工作总结了2205例无眼科疾病患者（4410只眼）的数据，这些患者使用眼反应分析仪进行了眼部生物力学检查。
已确定纤维膜层生物力学参数的正常范围。中央角膜厚度显示出相当大的变化（从448至685微米，平均为563±37微米）。此外，角膜阻力因子、角膜滞后和角膜弹性系数显示出几乎相等的均值，且随年龄增长而降低。
