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治疗闭塞性动静脉血液透析移植物的新型混合手术

New hybrid procedures in treating occluded arteriovenous hemodialysis grafts.

作者信息

Bachleda Petr, Janeckova Jana, Xinopulos Pavel, Smakal Oldrich

机构信息

Department of Surgery II - Vascular and Transplantation Surgery, University Hospital Olomouc, Czech Republic.

Department of Urology, University Hospital Olomouc, Czech Republic.

出版信息

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Mar;160(1):149-52. doi: 10.5507/bp.2015.068. Epub 2016 Feb 3.

Abstract

BACKROUND

The use of arteriovenous graft is indicated in patients if the subcutaneous venous bed is exhausted or unsuitable for arteriovenous fistula creation. The leading cause of failure of a prosthetic arteriovenous hemodialysis-access graft is venous anastomotic stenosis causing thrombosis of the graft. A number of surgical techniques and endovascular tools have been used to treat this stenosis and thrombosis. None have yet proven to be ideal. This study was designed to evaluate the results of hybrid treatment of arteriovenous graft thrombosis associated with venous anastomotic stenosis.

METHODS

Over the period 2013-2014, we treated 16 AVG occlusions. Immediately after the diagnosis of occlusion was made, the patients underwent thrombectomy using a Fogarty catheter. After thrombectomy, a diagnostic fistulogram was performed and if VAG stenosis was confirmed, it was treated with balloon angioplasty and stent graft introduction. Lesions were dilated to reduce the stenosis in the treated area to less than 25%.

RESULTS

Primary patency after 12 months was 32.8%. Primary assisted patency was 44.7%, secondary patency was 47.6%. Restenosis of the stent graft was seen in two patients. Recurring AVG occlusion was observed in four patients. The average number of interventions to maintain AVG patency was 1.18 per patient/1 year of dialysis.

CONCLUSION

Treatment of AVG thrombosis due to VAG stenosis by hybrid procedure proved to be effective and improved secondary patency.

摘要

背景

如果皮下静脉床已用尽或不适于建立动静脉内瘘,则对患者使用动静脉移植物。人工血管动静脉血液透析通路移植物失败的主要原因是静脉吻合口狭窄导致移植物血栓形成。已经使用了多种外科技术和血管内工具来治疗这种狭窄和血栓形成。但尚无一种被证明是理想的。本研究旨在评估与静脉吻合口狭窄相关的动静脉移植物血栓形成的混合治疗结果。

方法

在2013年至2014年期间,我们治疗了16例动静脉移植物闭塞。在诊断出闭塞后,立即使用Fogarty导管对患者进行血栓切除术。血栓切除术后,进行诊断性瘘管造影,如果确认存在动静脉移植物狭窄,则用球囊血管成形术和植入覆膜支架进行治疗。扩张病变以将治疗区域的狭窄减少至小于25%。

结果

12个月后的初级通畅率为32.8%。初级辅助通畅率为44.7%,次级通畅率为47.6%。两名患者出现覆膜支架再狭窄。四名患者观察到动静脉移植物再次闭塞。维持动静脉移植物通畅的平均干预次数为每名患者/每年透析1.18次。

结论

通过混合手术治疗因动静脉移植物狭窄导致的动静脉移植物血栓形成被证明是有效的,并提高了次级通畅率。

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